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Food Quote by David Perlmutter

“Inflammation, which you know by now is the cornerstone of many brain disorders, can be initiated when the immune system reacts to a substance in a person’s body. When antibodies of the immune system come into contact with a protein or antigen to which a person is allergic, the inflammatory cascade…” quote by David Perlmutter
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““Inflammation, which you know by now is the cornerstone of many brain disorders, can be initiated when the immune system reacts to a substance in a person’s body. When antibodies of the immune system come into contact with a protein or antigen to which a person is allergic, the inflammatory cascade is provoked, releasing a whole host of damaging chemicals known as cytokines. Gluten sensitivity in particular is caused by elevated levels of antibodies against the gliadin component of gluten. When the antibody combines with this protein (creating an anti-gliadin antibody), specific genes are turned on in a special type of immune cell in the body. Once these genes are activated, inflammatory cytokine chemicals collect and can attack the brain. Cytokines are highly antagonistic to the brain, damaging tissue and leaving the brain vulnerable to dysfunction and disease — especially if the assault continues.””

David Perlmutter

About This Quote

Source Book: Grain Brain, 2013

Immune reactions to gluten can trigger inflammation that damages brain tissue, linking gluten sensitivity to neurological disorders.

In simple terms: Gluten can cause brain‑damaging inflammation.

Key Takeaway

Consider testing for gluten sensitivity if experiencing neurological issues.

Themes

health nutrition immunology

Mood

informative cautious

Type

medical educational

When to use this quote

  • dietary changes
  • medical testing
  • patient education
  • research studies

Key Concepts

autoimmunity neuroinflammation

Questions to Reflect On

  • Should you screen for gluten sensitivity in cognitive decline?
  • How does diet influence neuroinflammation?
A Different Perspective

Not all brain disorders stem from gluten; individual variation exists.

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