““The physiology of inactivity theory suggests that prolonged sitting also causes weight gain by creating imbalances in critical metabolic hormones such as leptin, which regulates appetite and fat metabolism in the body. When leptin signaling is compromised, your brain will crave more food, and your body will default into a fat-storage hormonal pattern instead of a fat-burning hormonal pattern.17 All this has scientists and members of the medical community repeating the same tagline: sitting is the new smoking.””