““Opiates don't only relieve physical pain, they also relieve emotional pain. It turns out that the same part of the brain that experiences the suffering of physical pain also experiences the suffering of social rejection, for example. The sources and pathways of the pain are different, but the suffering is experienced in the same part of the brain, where opiate receptors are abudantly present. And if you look at alcohol, it's a pain-reliever. In fact, you know, the old saying, when someone drank too much they used to say "he's feeling no pain". Cocaine.. is a local anesthetic it numbs nerve endings. Cannabis has pain-relieving qualities. All the behaviors of addiction, whether they are substance-related or not, either directly soothe pain, emotional pain, or they distract from it. So my mantra and the first question in addiction is not "why the addiction?", but "why the pain?" And if want to understand why people have pain, you got to look at their lives, not at their genes, not at their choices, but what actually happened to them.””