““Jesse I first saw Jesse after she split from her husband. During a fight, she pulled a knife on him and told him not to go to sleep. He left her that evening. It turned out that Jesse had long-standing temper issues that paralleled her menstrual cycle. Regularly in the week before her period started, she became moody, anxious, and aggressive. And she aggravated the problem by drinking a lot. The incident with the knife had occurred at precisely this point in her cycle. When Jesse came to see me, I knew it would be helpful to find out what was going on in her brain.””