Acid Quote by Francis Crick
“The meaning of this observation is unclear, but it raises the unfortunate possibility of ambiguous triplets; that is, triplets which may code more than one amino acid. However one would certainly expect such triplets to be in a minority.”
About This Quote
Source Paper: The Genetic Code, 1961
Ambiguous codons could encode multiple amino acids, but they are expected to be rare.
In simple terms: Some codons might code for more than one amino acid, but they should be few.
Recognize and investigate rare genetic ambiguities.
Themes
Mood
Type
When to use this quote
- research on genetic mutations
- bioinformatics analysis
- evolutionary studies
Key Concepts
Questions to Reflect On
- How could ambiguous codons affect protein function?
- What methods can detect rare codon variants?
Ambiguity may be overestimated without extensive data.