It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion… — Francis Crick Copy Share Image
Attempts have been made from a study of the changes produced by mutation to obtain the relative order of the bases within… — Francis Crick Copy Share Image
It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code… — Francis Crick Copy Share Image
If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect… — Francis Crick Copy Share Image
A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a… — Francis Crick Copy Share Image
The meaning of this observation is unclear, but it raises the unfortunate possibility of ambiguous triplets; that is, triplets which may code… — Francis Crick Copy Share Image
Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were… — Francis Crick Copy Share Image
The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at… — Francis Crick Copy Share Image
It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another,… — Francis Crick Copy Share Image
In my experience most mathematicians are intellectually lazy and especially dislike reading experimental papers. He seemed to have very strong biological intuitions but unfortunately… — Francis Crick Copy Share Image
The major credit I think Jim and I deserve ... is for selecting the right problem and sticking to it. It's true that by… — Francis Crick Copy Share Image
“It is one of the striking generalizations of biochemistry—which surprisingly is hardly ever mentioned in the biochemical text-books—that the twenty amino acids and the… — Francis Crick Copy Share Image
The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry. — Francis Crick Copy Share Image
One of the most frightening things in the Western world, and in this country in particular, is the number of people who believe in… — Francis Crick Copy Share Image
For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and… — Francis Crick Copy Share Image
There is no form of prose more difficult to understand and more tedious to read than the average scientific paper. — Francis Crick Copy Share Image
Finally one should add that in spite of the great complexity of protein synthesis and in spite of the considerable technical difficulties in synthesizing… — Francis Crick Copy Share Image
Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were only one… — Francis Crick Copy Share Image
