Amount Quote by Paul Greengard
“Mice deficient in this protein, called p11, display depression-like behaviors, while those with sufficient amounts behave as if they have been treated with antidepressants.”
About This Quote
Source Journal Article: Neuropsychopharmacology, 2005
Low p11 protein in mice leads to depression-like behavior; sufficient p11 mimics antidepressant effects.
In simple terms: p11 deficiency causes depressive traits; enough p11 acts like medication.
Target p11 pathways for depression treatment.
Themes
Mood
Type
When to use this quote
- preclinical research
- drug development
- animal models
Key Concepts
Questions to Reflect On
- How might p11 modulation translate to human therapies?
- What other factors interact with p11?
Human depression is more complex than a single protein.