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“Mice deficient in this protein, called p11, display depression-like behaviors, while those with sufficient amounts behave as if they have been treated with antidepressants.” quote by Paul Greengard
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“Mice deficient in this protein, called p11, display depression-like behaviors, while those with sufficient amounts behave as if they have been treated with antidepressants.”

Paul Greengard

About This Quote

Source Journal Article: Neuropsychopharmacology, 2005

Low p11 protein in mice leads to depression-like behavior; sufficient p11 mimics antidepressant effects.

In simple terms: p11 deficiency causes depressive traits; enough p11 acts like medication.

Key Takeaway

Target p11 pathways for depression treatment.

Themes

neuroscience mental health proteinetics

Mood

analytical hopeful

Type

scientific clinical

When to use this quote

  • preclinical research
  • drug development
  • animal models

Key Concepts

protein regulation behavioral neuroscience

Questions to Reflect On

  • How might p11 modulation translate to human therapies?
  • What other factors interact with p11?
A Different Perspective

Human depression is more complex than a single protein.

2.2 out of 5 (3 ratings)

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