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Cholesterol Quote by David Perlmutter, M.D

“Nothing could be further from the truth than the myth that if we lower our cholesterol levels we might have a greater chance of living longer and healthier lives. In a recent report appearing in the prestigious medical journal the _Lancet_, researchers from the Netherlands studied 724 elderly…” quote by David Perlmutter, M.D
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““Nothing could be further from the truth than the myth that if we lower our cholesterol levels we might have a greater chance of living longer and healthier lives. In a recent report appearing in the prestigious medical journal the _Lancet_, researchers from the Netherlands studied 724 elderly individuals whose average age was eighty-nine years and followed them for ten years. What they found was truly extraordinary. During the study, 642 participants died. Each thirty-nine-point increase in total cholesterol corresponded to a 15 percent decrease in mortality risk. In the study, there was absolutely no difference in the risk of dying from coronary artery disease between the high- versus low-cholesterol groups, which is incredible when you consider the number of elderly folks who are taking powerful cholesterol-lowering drugs. Other common causes of death in the elderly were found to be dramatically associated with lower cholesterol. The authors reported: 'Mortality from cancer and infection was significantly lower among the participants in the highest total cholesterol category than in the other categories, which largely explains the lower all-cause mortality in this category.' In other words, people with the highest total cholesterol were less likely to die from cancer and infections -- common fatal illnesses in older folks -- than those with the lowest cholesterol levels. In fact, when you compare the lowest- and highest-cholesterol groups, the risk of dying during the study was reduced by a breathtaking 48 percent in those who had the highest cholesterol. High cholesterol can extend longevity. ~ David Perlmutter, M.D., _Grain Brain_””

David Perlmutter, M.D

About This Quote

Source Book: Grain Brain by David Perlmutter, 2013

Higher cholesterol in very elderly may correlate with lower mortality from cancer and infection, suggesting a complex health relationship.

In simple terms: High cholesterol might be linked to longer life in seniors.

Key Takeaway

Reevaluate blanket cholesterol‑lowering advice for the elderly.

Themes

health aging cholesterol longevity

Mood

cautious inquisitive

Type

scientific analytical

When to use this quote

  • elderly care
  • medical guidelines
  • dietary counseling
  • clinical research

Key Concepts

epidemiology risk assessment nutritional science

Questions to Reflect On

  • Should cholesterol targets differ by age?
  • What other lifestyle factors affect elderly mortality?
A Different Perspective

Observational data; not prove causation; other factors may influence outcomes.

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