Cancer research Quote by Paul A. Offit
““In 1996, investigators from the Fred Hutchinson Cancer Research Center in Seattle studied 18,000 people who, because they had been exposed to asbestos, were—like those who smoked cigarettes—also at greater risk of lung cancer. Participants were given large doses of vitamin A, beta-carotene, both, or neither. The study ended abruptly when the safety monitors realized that those taking megavitamins had a dramatically higher rate of lung cancer (28 percent greater than those not receiving vitamins) as well as heart disease (17 percent greater).””
About This Quote
Source Study: Clinical trial on vitamin A and beta‑carotene, Fred Hutchinson Cancer Research Center, 1996
High‑dose vitamins increased lung cancer and heart disease risk among asbestos‑exposed individuals, showing that more is not always better.
In simple terms: Megavitamins can be harmful.
Avoid excessive supplementation without evidence.
Themes
Mood
Type
When to use this quote
- clinical trial
- public health policy
- patient counseling
Key Concepts
Questions to Reflect On
- Should we trust supplement labels?
- How can we better assess supplement safety?
Higher doses may not translate to benefits and can cause harm.