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Death Quote by Jean-Louis Vincent

““The relationship between BP and mortality in patients with stroke may be “U-shaped.” According to this notion, systolic BP (SBP) values above or below 140 to 180 mm Hg are associated with increased mortality. In the International Stroke Trial, SBP above 200 mm Hg was associated with an increased…” quote by Jean-Louis Vincent
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““The relationship between BP and mortality in patients with stroke may be “U-shaped.” According to this notion, systolic BP (SBP) values above or below 140 to 180 mm Hg are associated with increased mortality. In the International Stroke Trial, SBP above 200 mm Hg was associated with an increased risk of recurrent ischemic stroke (50% greater risk of recurrence), while low BP (particularly <120 mm Hg) was associated with an excess number of deaths from coronary heart disease.””

Jean-Louis Vincent

About This Quote

Source Study: International Stroke Trial, 2002

Blood pressure shows a U‑shaped mortality curve after stroke; both high and low extremes increase risk.

In simple terms: Both very high and very low BP raise death risk after stroke.

Key Takeaway

Aim for moderate BP targets.

Themes

medicineiology stroke blood pressure mortality

Mood

analytical clinical

Type

evidence‑based informative

When to use this quote

  • hospital care
  • post‑stroke rehab
  • patient monitoring
  • risk assessment

Key Concepts

U‑shaped risk hemodynamics clinical guidelines

Questions to Reflect On

  • How do you determine optimal BP for each patient?
  • What factors shift the U‑shape?
A Different Perspective

Individual variability may require personalized targets.

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