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Chemical Reaction Quote by Brett Osborn

“Yes. There are a variety of reasons that we as humans age, one of which is oxidant stress from free radical formation. Known as the Free Radical Theory of Aging, this explanation was first proposed by Denham Harman in the 1950s. Other theories include unchecked inflammation, glycation, cell…” quote by Brett Osborn
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““Yes. There are a variety of reasons that we as humans age, one of which is oxidant stress from free radical formation. Known as the Free Radical Theory of Aging, this explanation was first proposed by Denham Harman in the 1950s. Other theories include unchecked inflammation, glycation, cell membrane and DNA damage. Interestingly, they are interrelated as I will explain. Every cell in our body requires energy for a variety of processes. The production of such cellular energy or ATP (adenosine triphosphate) is occurring at the molecular level, unbeknownst to you, billions of times per second, in cellular structures known as mitochondria. Through a complex series of chemical reactions, electrons are ultimately transferred to oxygen, driving the formation of ATP molecules. No oxygen, no electron receptor, death ensues. (Note: Cyanide poisons this so-called “electron transport chain” often times resulting in death.) This process of ATP generation is imperfect.””

Brett Osborn

About This Quote

Source Lecture: Aging Biology, 2020

A detailed explanation of the Free Radical Theory of Aging and related cellular damage mechanisms.

In simple terms: Free radicals cause aging and other damage.

Key Takeaway

Address oxidative stress to promote health.

Themes

biology aging cellular health science

Mood

informative analytical serious

Type

educational scientific

When to use this quote

  • research presentation
  • academic lecture
  • health education
  • science communication

Key Concepts

free radicals mitochondria DNA damage inflammation

Questions to Reflect On

  • How can we mitigate oxidative stress?
  • What other aging theories complement this?
A Different Perspective

The theory is one of many and not universally accepted.

3.7 out of 5 (9 ratings)

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