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Animal Quote by Bernard Brodie

“Various species of animals react differently to the same drug. Not only do the variations in the metabolism of a drug make it difficult to extrapolate results of animal experiments to man but they create a serious obstacle to the development of new therapeutic drugs.” quote by Bernard Brodie
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“Various species of animals react differently to the same drug. Not only do the variations in the metabolism of a drug make it difficult to extrapolate results of animal experiments to man but they create a serious obstacle to the development of new therapeutic drugs.”

Bernard Brodie

About This Quote

Animal drug metabolism varies, making human predictions difficult and hindering new drug development.

In simple terms: Different species react differently to drugs, complicating research.

Key Takeaway

Account for cross‑species differences in drug testing.

Themes

pharmacology research development

Mood

cautious analytical

Type

scientific technical

When to use this quote

  • drug discovery
  • preclinical studies
  • regulatory planning

Key Concepts

metabolism species variation clinical translation

Questions to Reflect On

  • What alternatives improve human relevance?
  • How can we better model interspecies differences?
A Different Perspective

Animal models may not fully predict human outcomes.

2.5 out of 5 (4 ratings)

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