Animal Quote by Bernard Brodie
“Various species of animals react differently to the same drug. Not only do the variations in the metabolism of a drug make it difficult to extrapolate results of animal experiments to man but they create a serious obstacle to the development of new therapeutic drugs.”
About This Quote
Animal drug metabolism varies, making human predictions difficult and hindering new drug development.
In simple terms: Different species react differently to drugs, complicating research.
Account for cross‑species differences in drug testing.
Themes
Mood
Type
When to use this quote
- drug discovery
- preclinical studies
- regulatory planning
Key Concepts
Questions to Reflect On
- What alternatives improve human relevance?
- How can we better model interspecies differences?
Animal models may not fully predict human outcomes.