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Addiction Quote by Robert M. Sapolsky

“This explains context-dependent craving in addiction.93 Suppose an alcoholic has been clean and sober for years. Return him to where the alcohol consumption used to occur (e.g., that rundown street corner, that fancy men’s club), and those potentiated synapses, those cues that were learned to be…” quote by Robert M. Sapolsky
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““This explains context-dependent craving in addiction.93 Suppose an alcoholic has been clean and sober for years. Return him to where the alcohol consumption used to occur (e.g., that rundown street corner, that fancy men’s club), and those potentiated synapses, those cues that were learned to be associated with alcohol, come roaring back into action, dopamine surges with anticipation, and the craving inundates.””

Robert M. Sapolsky

About This Quote

Source Book: The Biological Basis of Behavior, 2020

Environmental cues linked to past substance use can trigger intense cravings even after long abstinence, due to strengthened neural pathways.

In simple terms: Old places can spark strong cravings.

Key Takeaway

Avoid high‑risk environments.

Themes

addiction neuroscience environmental triggers relapse prevention

Mood

cautious hopeful

Type

educational preventive

When to use this quote

  • rehab counseling
  • support groups
  • urban settings
  • relapse monitoring

Key Concepts

conditioned learning dopamine response habit formation

Questions to Reflect On

  • How can one rewire these cue associations?
  • What strategies reduce cue‑induced relapse?
A Different Perspective

Cravings may persist despite years of sobriety.

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