““A half century after Nidetch’s Mallomar binges, scientists had developed a technology that could see cravings erupting, like solar flares, inside the human brain. In early 2008, a research team at the Lewis Center for Neuroimaging at the University of Oregon measured just such a craving in a nineteen-year-old college student we will call Debbie. Debbie had her head inside a very large, very expensive round magnet called an MRI scanner when an image of a chocolate milk shake was flashed before her eyes for two seconds. As soon as Debbie saw it, certain parts of her brain became “activated,” which is to say they drew in lots of blood as millions of neurons were fired. These regions—the left medial orbitofrontal cortex, anterior cingulate cortex, and three other small, curly pockets of gray matter—are all associated with “motivation.” And the functional MRI (fMRI) showed them glowing a bright yellowy orange, like coals in a hot fire, indicating those parts of her brain were churning through quite a lot of blood. She was experiencing “incentive salience,” the scientific term for a Frankenstein craving, or a heightened state of “wanting.” Debbie got what she wanted.””
