““who are always right, and are given to reminding us of it, are irritating; prophets are irritating, and Owen Meany is decidedly a prophet. Because I don’t start a novel until I know the ending, every novel of mine is predestined. In A Prayer for Owen Meany, it was not that much of a stretch to make the main character aware (to some degree) of his own predestination. After all, I am always aware of the predestination of my characters. In Owen’s case, he bears the terrible burden of foreseeing his own death. His tenacious faith tells him that even his death—like his size, like his voice, like practicing the shot—is for a reason. Separate from the Vietnam background and the apparent religious miracle, A Prayer for Owen Meany is also a novel about the loss of childhood, which I thought was best signified by the loss of a childhood friend. People are always losing things in my novels—not just, as Johnny Wheelwright does, a finger and a mother and a best friend. In my first novel, Setting Free the Bears, another best friend is lost—stung to death by bees! In my second and third novels, The Water-Method Man and The 158-Pound””