“ketones block the apoptotic pathway that would otherwise lead to self-destruction of brain cells.” — David Perlmutter Copy Share Image
“when the omega-3 fats EPA and DHA are oxidized, they significantly activate the Nrf2 pathway. For” — David Perlmutter Copy Share Image
“often a fully preventable problem. If you’re a chronic headache sufferer, why not try a gluten-free diet? What have you got to… — David Perlmutter Copy Share Image
“walnut oil, were 60 percent less likely to develop dementia than those who did not regularly consume such oils. The” — David Perlmutter Copy Share Image
“statins may lessen brain function and increase risk for heart disease. The reason is simple: The brain needs cholesterol” — David Perlmutter Copy Share Image
The biggest issue by far is that carbohydrates are absolutely at the cornerstone of all of our major degenerative conditions. — David Perlmutter Copy Share Image
“people who start taking cholesterol-lowering medication (i.e., statins) can become much more depressed.” — David Perlmutter Copy Share Image
“I’ve had plenty more patients come through my doors and leave with a pain-free head, thanks to the adoption of a gluten-free… — David Perlmutter Copy Share Image
“The gene that turns on BDNF is activated by a variety of lifestyle habits, including physical exercise, caloric restriction, following a ketogenic… — David Perlmutter Copy Share Image
Carbohydrates, whether derived from gluten-containing foods or other sources, including fruit, sweetened beverages, and starchy vegetables, are dangerous as they relate to… — David Perlmutter Copy Share Image
“As Dr. Gao reported, “Our data support the hypothesis that the formation of… compounds generated from oxidation of EPA and DHA in… — David Perlmutter Copy Share Image
“DHA, is its role in regulating gene expression for the production of BDNF. Put simply, DHA helps orchestrate the production, connectivity, and… — David Perlmutter Copy Share Image
“reduce the risk of LDL oxidation—not necessarily levels of LDL itself. A principal player in that risk of oxidation is higher levels… — David Perlmutter Copy Share Image
“Indeed, Dr. Cahill and other researchers have determined that beta-HBA, which is easily obtainable just by adding coconut oil to your diet,… — David Perlmutter Copy Share Image
“The bottom line is that if you want to reduce oxidative stress and the action of free radicals harming your brain, you… — David Perlmutter Copy Share Image
“they gave twenty-four students resveratrol and recorded marked increases in blood flow in the brain while they were performing mental tasks. And… — David Perlmutter Copy Share Image
“But a caveat: Once free radicals damage the LDL molecule, it’s rendered much less capable of delivering cholesterol to the brain. In… — David Perlmutter Copy Share Image
Researchers have known for some time now that the cornerstone of all degenerative conditions, including brain disorders, is inflammation. But what they… — David Perlmutter Copy Share Image
The origin of brain disease is in many cases predominantly dietary. Although several factors play into the genesis and progression of brain… — David Perlmutter Copy Share Image
“The following ingredients are often code for gluten: amino peptide complex Avena sativa brown rice syrup caramel color (frequently made from barley)… — David Perlmutter Copy Share Image
“It’s well documented that glycated hemoglobin is a powerful risk factor for diabetes, but it’s also been correlated with risk for stroke,… — David Perlmutter Copy Share Image
“The bile salts secreted by the gallbladder, which are needed for the digestion of fat and, therefore, the absorption of fat-soluble vitamins… — David Perlmutter Copy Share Image
“The only way to stop this internal pathway run amok is to consume an adequate amount of dietary cholesterol and back way… — David Perlmutter Copy Share Image
“The following grains and starches are gluten-free: amaranth arrowroot buckwheat corn millet potato quinoa rice sorghum soy tapioca teff The following foods… — David Perlmutter Copy Share Image
The idea that people are nutritionally deprived because they don't eat grain has no scientific basis. — David Perlmutter Copy Share Image
“Fat—not carbohydrate—is the preferred fuel of human metabolism and has been for all of human evolution. We” — David Perlmutter Copy Share Image
The story of gluten as it relates to the brain throws a wide net, so much more encompassing than the inflammation of… — David Perlmutter Copy Share Image
“Nine times out of ten, people pick the wrong food. No, it’s not the sugar (GI = 68), it’s not the candy… — David Perlmutter Copy Share Image
“gluten breaks down in the stomach to become a mix of polypeptides that can cross the blood-brain barrier. Once they gain entry,… — David Perlmutter Copy Share Image
“removal of gluten from the diet and the adoption of a grain-brain-free way of life is often the surest ticket to relief… — David Perlmutter Copy Share Image
“So what happens if you restrict your cholesterol intake, as so many people do today? The body sends out an alarm that… — David Perlmutter Copy Share Image
“Coconut oil, from which we derive MCTs, is a rich source of an important precursor molecule for beta-hydroxybutyrate and is a helpful… — David Perlmutter Copy Share Image
“THE GLUTEN POLICE The following grains and starches contain gluten: barley bulgur couscous farina graham flour kamut matzo rye semolina spelt triticale… — David Perlmutter Copy Share Image
“consumption of omega-3 oils actually counterbalanced the detrimental effect of the omega-6 oils, and cautioned against eating omega-6 oils in the absence… — David Perlmutter Copy Share Image
The food we eat goes beyond its macronutrients of carbohydrates, fat and protein. It's information. It interacts with and instructs our genome… — David Perlmutter Copy Share Image
The best diet for overall health, and specifically for heart, brain, and cancer risk reduction, is a diet that's aggressively low in… — David Perlmutter Copy Share Image
“We can break down fat into specialized molecules called ketones, and one in particular that I’ve already mentioned—beta-hydroxybutyrate (beta-HBA)—is a superior fuel… — David Perlmutter Copy Share Image
Our ancestors relied upon their advanced brains to survive during times of food shortage, and fortunately, the human brain is able to… — David Perlmutter Copy Share Image
Rarely, Type 2 diabetes develops without any readily identifiable predisposing factor. But in the great majority of cases, it is brought on… — David Perlmutter Copy Share Image
So-called 'complex carbs' may actually represent a more significant threat to health than simple sugar in that they may not only raise… — David Perlmutter Copy Share Image
“if you cannot control your hunger and appetite, good luck managing your blood chemistry, metabolism, waistline, and, in the bigger picture, the prospect of… — David Perlmutter Copy Share
“Nine times out of ten, people pick the wrong food. No, it’s not the sugar (GI = 68), it’s not the candy bar (GI… — David Perlmutter Copy Share
“Your brain… weighs three pounds and has one hundred thousand miles of blood vessels. contains more connections than there are stars in the Milky… — David Perlmutter Copy Share
Inflammation is the cornerstone of Alzheimer's disease and Parkinson's, multiple sclerosis - all of the neurodegenerative diseases are really predicated on inflammation. — David Perlmutter Copy Share
“Those who experience symptoms complain of abdominal pain, nausea, diarrhea, constipation, and intestinal distress. Some people, however, don’t experience obvious signs of gastrointestinal trouble,… — David Perlmutter Copy Share
Saturated fat is a fundamental building block for brain cells. It's certainly interesting to consider that one of the richest sources of saturated fat… — David Perlmutter Copy Share
“THE GLUTEN POLICE The following grains and starches contain gluten: barley bulgur couscous farina graham flour kamut matzo rye semolina spelt triticale wheat wheat… — David Perlmutter Copy Share
“people with celiac have significantly increased production of free radicals, and they exhibit free radical damage to their fat, protein, and even DNA.16 In… — David Perlmutter Copy Share
“The bile salts secreted by the gallbladder, which are needed for the digestion of fat and, therefore, the absorption of fat-soluble vitamins like A,… — David Perlmutter Copy Share
“According to the latest research, we owe our tremendous brains to the need to think… and the need to run.” — David Perlmutter Copy Share
Most grain foods, whether we're talking about quinoa, amaranth, the very popular grains of the day - the reality is they still are associated… — David Perlmutter Copy Share
“reduce the risk of LDL oxidation—not necessarily levels of LDL itself. A principal player in that risk of oxidation is higher levels of glucose;… — David Perlmutter Copy Share
People are getting to this place of understanding that their lifestyle choices actually do matter a whole lot as opposed to this notion that… — David Perlmutter Copy Share
“What you eat & when you eat matter, but so does what order you eat your foods in. Never eat what Dr. Casey Means… — David Perlmutter Copy Share
“The results of the study revealed that those individuals in the lowest 10 percent of daily physical activity had a 230 percent increased risk… — David Perlmutter Copy Share