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Mental illness Quote by Siddhartha Mukherjee

“Finally, some of the genes identified in certain variants of schizophrenia or bipolar disease actually augment certain abilities. If the most pathological variant of a mental illness can be sifted out or discriminated from the high-functioning variants by genes or gene combinations alone, then we…” quote by Siddhartha Mukherjee
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““Finally, some of the genes identified in certain variants of schizophrenia or bipolar disease actually augment certain abilities. If the most pathological variant of a mental illness can be sifted out or discriminated from the high-functioning variants by genes or gene combinations alone, then we can hope for such a test. But it is much more likely that such a test will have inherent limits: most of the genes that cause disease in one circumstance might be the very genes that cause hyperfunctional creativity in another. As Edvard Munch put it, "[My troubles] are part of me and my art. They are indistinguishable from me, and [treatment] would destroy my art. I want to keep those sufferings." These very "sufferings," we might remind ourselves, were responsible for one of the most iconic images of the twentieth century-of a man so immersed in a psychotic era that he could only scream a psychotic response to it.””

Siddhartha Mukherjee

About This Quote

Source Interview: The Gene: A Deep History of Heredity, 2021

Genetic variants linked to mental illness can also enhance creativity, making diagnostic tests ethically complex.

In simple terms: Some disease genes may boost talent, so testing is limited.

Key Takeaway

Recognize the dual nature of genetics.

Themes

genetics creativity ethics mental health

Mood

thoughtful cautious

Type

philosophical scientific

When to use this quote

  • clinical diagnostics
  • artistic pursuits
  • personal identity
  • therapy decisions

Key Concepts

pleiotropy gene‑environment interaction neurodiversity

Questions to Reflect On

  • How do we balance early detection with preserving creative potential?
  • Can we develop nuanced assessments that differentiate harmful from beneficial gene effects?
A Different Perspective

A test may label beneficial traits as pathological, risking loss of unique abilities.

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