Change Quote by Robert M. Sapolsky
““As emphasized in the last chapter, epigenetic changes can be multi-generational.8 Dogma was that all the epigenetic marks (i.e., changes in the DNA or surrounding proteins) were erased in eggs and sperm. But it turns out that epigenetic marks can be passed on by both (e.g., make male mice diabetic, and they pass the trait to their offspring via epigenetic changes in sperm).””
About This Quote
Source Book: Behave: The Biology of Humans at Our Best and Worst, Robert M. Sapolsky, 2017
Epigenetic modifications can survive the germ line and influence traits in subsequent generations, challenging the belief they are always reset.
In simple terms: Epigenetic marks can be inherited across generations.
Key Takeaway
Consider how lifestyle choices may affect future generations.
Themes
biology
inheritance
epigenetics
generational health
Mood
thoughtful
analytical
Type
scientific
educational
When to use this quote
- parental diet
- environmental exposures
- research studies
- public health policy
Key Concepts
DNA methylation
histone modification
transgenerational transmission
Questions to Reflect On
- What behaviors might you change to benefit your descendants?
- How robust is the evidence for human transgenerational epigenetics?
A Different Perspective
Not all epigenetic changes are stable; many are reversible or context‑dependent.
