Skip to content

Change Quote by Jerome Groopman

“Researchers are learning that a change in mind-set has the power to alter neurochemistry. Belief and expectation—the key elements of hope—can block pain by releasing the brain’s endorphins and enkephalins, mimicking the effects of morphine.” quote by Jerome Groopman
Download Open image
““Researchers are learning that a change in mind-set has the power to alter neurochemistry. Belief and expectation—the key elements of hope—can block pain by releasing the brain’s endorphins and enkephalins, mimicking the effects of morphine.””

Jerome Groopman

About This Quote

Source Article: “The Power of Expectation” by Jerome Groopman, 2015

Belief and expectation can trigger endogenous opioids, reducing pain similarly to morphine.

In simple terms: Hope can physically lessen pain.

Key Takeaway

Cultivate hopeful expectations for health.

Themes

health pain management neuroscience hope

Mood

optimistic scientific

Type

educational motivational

When to use this quote

  • clinical practice
  • patient counseling
  • mind‑body therapies
  • self‑care routines

Key Concepts

placebo effect neurochemistry psychoneuroimmunology

Questions to Reflect On

  • How can you integrate hope into medical care?
  • What limits exist for mind‑body pain relief?
A Different Perspective

Hope alone may not replace medical treatment for severe conditions.

4.1 out of 5 (9 ratings)

More by Jerome Groopman

Explore all 26 Jerome Groopman quotes

More Change quotes

Browse all 33,920 Change quotes