““Part of this problem lies with how we do ‘science’. The paradigm of ‘modern science’ is that we isolate each individual factor and study it in isolation. This is the ‘reductionist’ approach to discovering scientific truth. This is straight forward and relatively easy to do, so lots of scientists swear by it. But what if a clinical problem like insulin resistance is not due to a single domino, but rather a number of dysfunctional proteins or other structural materials in combination? The answer – the reductionist approach can’t deliver an answer in this situation. If multiple steps in a pathway, working in varying combinations, eventually compromise that pathway’s action, the reductionist paradigm fails. But if one takes a more holistic or cosmopolitan approach to assessing the problem, the cause of the problem might be better appreciated.””
![“In the past, [medicalization]has been portrayed as something that doctors inflict on a passive and un-suspecting world - an expansion of the Medical Empire. But in reality, it seems that these reductionist bio-medical stories can appeal to us all, because complex problems often have…” quote by Ben Goldacre](https://sms4smile.com/quotes/img-quotes/84e/ben-goldacre-9578_appeals_in-the-past-medicalization-has-been-port_921552.jpg)
![“The situation with regard to insulin is particularly clear. In many parts of the world diabetic children still die from lack of this hormone. ... [T]hose of us who search for new biological facts and for new and better therapeutic weapons should appreciate that one of the central problems of the…” quote by Charles Herbert Best](https://sms4smile.com/quotes/img-quotes/db9/charles-herbert-best-187634_africa_the-situation-with-regard-to-insulin-is_2462751.jpg)
