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Acid Quote by Francis Crick

“How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.” quote by Francis Crick
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“How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.”

Francis Crick

About This Quote

Source Scientific Lecture: Molecular Biology, 1961

Codons are read in groups of three nucleotides, a pattern inferred from protein synthesis despite no explicit markers.

In simple terms: DNA is read in three‑letter units called codons.

Key Takeaway

Recognize three‑base groupings in genetic sequences.

Themes

genetics DNA translation

Mood

analytical educational

Type

scientific technical

When to use this quote

  • gene editing
  • bioinformatics education
  • research analysis

Key Concepts

triplet code reading frame

Questions to Reflect On

  • How does the cell ensure correct codon reading?
  • What mechanisms prevent frame shifts?
A Different Perspective

The lack of physical separators can cause reading errors.

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