““Most animals can't tap into these open-source adaptations deliberately. The flies didn't seek out Spiroplasma to solve their worm problem. Woodrats didn't go looking for the creosote-defusing microbes so they could widen their diet. They must rely on luck to endow them with the right partners. But we humans aren't so restricted. We are innovators, planners, and problem-solvers. And we have one huge advantage that all other animals lack: we know that microbes exist! We have devised instruments that can see them. We can deliberately grow them. We have tools that can decipher the rules that govern their existence, and the nature of their partnerships with us. And that gives us the power to manipulate those partnerships intentionally. We can replace faltering communities of microbes with new ones that will lead to better health. We can create new symbioses that fight disease. And we can break age-old alliances that threaten our lives.””