“Any extrapolation of history into the future presupposes an environment of static discovery—an oxymoron.” — Siddhartha Mukherjee Copy Share Image
“We hung our heads, ashamed. It was, I suspected, not the first time that a patient had consoled a doctor about the… — Siddhartha Mukherjee Copy Share Image
“Six decades and two years, no more than a passing glance of time, separate Mendel's initial experiments on peas and the court-mandated… — Siddhartha Mukherjee Copy Share Image
“Mutants are necessary to maintain the essence of our selves. Our genomes has negotiated a fragile balance between counterpoised forces, pairing strand… — Siddhartha Mukherjee Copy Share Image
Sandeep Jauhar’s Doctored is a passionate and necessary book that asks difficult questions about the future of medicine. The narrative is gripping,… — Siddhartha Mukherjee Copy Share Image
“It lives desperately, inventively, fiercely, territorially, cannily, and defensively--at times, as if teaching us how to survive. To confront cancer is to… — Siddhartha Mukherjee Copy Share Image
What does it mean to be an oncologist? It means that you get to sit in at a moment of another person's… — Siddhartha Mukherjee Copy Share Image
“It has repeated elements that appear frequently. A pesky, mysterious three-hundred-base-pair sequence called Alu appears and reappears tens of thousands of times,… — Siddhartha Mukherjee Copy Share Image
“In the folklore of science, there is the often-told story of the moment of discovery: the quickening of the pulse, the spectral… — Siddhartha Mukherjee Copy Share Image
“It is encrusted with history. Embedded within it are peculiar fragments of DNA-some derived from ancient viruses-that were inserted into the genome… — Siddhartha Mukherjee Copy Share Image
“Suppose, Paley wrote, a man walking across a heath happens upon a watch lying on the ground. He picks up the instrument… — Siddhartha Mukherjee Copy Share Image
“Although we fully understand the genetic code-i.e., how the information in a single gene is used to build a protein-we comprehend virtually… — Siddhartha Mukherjee Copy Share Image
“Perhaps the most striking illustration of Bayes’s theorem comes from a riddle that a mathematics teacher that I knew would pose to… — Siddhartha Mukherjee Copy Share Image
“As Muller thought about the future of eugenics and the possibility of altering human genomes, he wondered whether Galton and his collaborators… — Siddhartha Mukherjee Copy Share Image
“A note of caution: epigenetics is also on the verge of transforming into a dangerous idea. Epigenetic modifications of genes can potentially superpose historical… — Siddhartha Mukherjee Copy Share
When you immerse yourself in medicine you realise that hope is not absolute. It's not that simple. — Siddhartha Mukherjee Copy Share
“I had a novice's hunger for history, but also a novice's inability to envision it.” — Siddhartha Mukherjee Copy Share
“Any extrapolation of history into the future presupposes an environment of static discovery—an oxymoron.” — Siddhartha Mukherjee Copy Share
“Six decades and two years, no more than a passing glance of time, separate Mendel's initial experiments on peas and the court-mandated sterilization of… — Siddhartha Mukherjee Copy Share
“We now know that cells have ancient detectors that recognize viral genes and stamp them with chemical marks, like cancellation signs, to prevent their… — Siddhartha Mukherjee Copy Share
“Familial schizophrenia (like normal human features such as intelligence and temperament) is thus highly heritable but only moderately inheritable. In other words, genes-hereditary determinants-are… — Siddhartha Mukherjee Copy Share
“If you prefer an “academic life” as a retreat from reality, do not go into biology. This field is for a man or woman… — Siddhartha Mukherjee Copy Share
“But the pigs--seventy pounds of porcine weight that did not take kindly to weekly endoscopies--did not sprout any ulcers. And testing the theory on… — Siddhartha Mukherjee Copy Share
“One of the four genes used by Yamanaka to reverse cellular fate is called c-myc. Myc, the rejuvenating factor, is no ordinary gene: it… — Siddhartha Mukherjee Copy Share
A breast cancer might turn out to have a close resemblance to a gastric cancer. And this kind of reorganization of cancer in terms… — Siddhartha Mukherjee Copy Share
“But in 1960, oncology was not yet ready for this proposal. Not until several years later did it strike the board that had fired… — Siddhartha Mukherjee Copy Share
“Mutants are necessary to maintain the essence of our selves. Our genomes has negotiated a fragile balance between counterpoised forces, pairing strand with opposite… — Siddhartha Mukherjee Copy Share
“Even an ancient monster needs a name. To name an illness is to describe a certain condition of suffering—a literary act before it becomes… — Siddhartha Mukherjee Copy Share
