Difficulties Quote by Isaac Newton

“The popular view that scientists proceed inexorably from well-established fact to well-established fact, never being influenced by any unproved conjecture, is quite mistaken. Provided…

— Andrew Hodges

The rules of scientific investigation always require us, when we enter the domains of conjecture, to adopt that hypothesis by which the greatest number…

— Matthew Fontaine Maury

If truth can be found in any sublunary science, numbers will produce it, for to that at last almost all other sciences refer for…

— Hester Lynch Piozzi

Occurrences which according to received theories ought not to happen, are the facts which serve as clues to new discoveries

— John Herschel

The art of discovering the causes of phenomena, or true hypotheses, is like the art of deciphering, in which an ingenious conjecture often greatly…

— Gottfried Leibniz

In real science a hypothesis can never be proved true...A science which confines itself to correlating phenomena can never learn anything about the reality…

— James Jeans

A good hypothesis in science must have other properties than those of the phenomenon it is immediately invoked to explain, otherwise it is not…

— William James

There is something fascinating about science. One gets such wholesale returns of conjecture out of such a trifling investment of fact.

— Mark Twain

Scientists often have a naive faith that if only they could discover enough facts about a problem, these facts would somehow arrange themselves in…

— Theodosius Dobzhansky

The entire annals of Observation probably do not elsewhere exhibit so extraordinary a verification of any theoretical conjecture adventured on by the human spirit!

— John Pringle Nichol

Hypotheses should be subservient only in explaining the properties of things but not assumed in determining them, unless so far as they may furnish…

— Isaac Newton

As long as scientists are free to pursue the truth wherever it may lead, there will be a flow of new scientific knowledge to…

— Vannevar Bush