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“kids whose brains have undergone epigenetic changes because of early adversity have an inflammation-pro-mot- drip of fight-or-flight hormones turned on high every day—and there is no off switch.” quote by Donna Jackson Nakazawa
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““kids whose brains have undergone epigenetic changes because of early adversity have an inflammation-pro-mot- drip of fight-or-flight hormones turned on high every day—and there is no off switch.””

Donna Jackson Nakazawa

About This Quote

Source Book: The Body Keeps the Score, 2015

Early trauma rewires the brain, causing a constant stress response with elevated fight‑or‑flight hormones and no natural calming mechanism.

In simple terms: Childhood adversity keeps the stress system stuck on high.

Key Takeaway

Address early trauma to restore physiological balance.

Themes

trauma biology stress response

Mood

empathetic hopeful

Type

scientific educational

When to use this quote

  • clinical therapy
  • parental support
  • school counseling
  • public health initiatives

Key Concepts

epigenetics neuroendocrinology psychology

Questions to Reflect On

  • What early signs indicate chronic stress?
  • How can we safely reset the stress response?
A Different Perspective

Not all individuals respond uniformly; interventions may need personalization.

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