““Vaccination has made smallpox extinct in the wild, as well as rinderpest, a relative of measles that affects cattle and buffalo, among others. Poliomyelitis, which has in its heyday killed and maimed millions of children and adults alike, is close to eradication, with fewer than 200 wild-type cases documented in 2020. Vaccines are some of the most effective public health interventions against infectious disease.””