Best Francis Crick Quotes
- A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of… Acid
- Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were only one triplet… Acid
- If poly A is added to poly U, to form a double or triple helix, the combination is inactive. Added
- Again the message to experimentalists is: Be sensible but don't be impressed too much by negative arguments. If at all possible, try it and see… All
- A theory should not attempt to explain all the facts, because some of the facts are wrong All
- If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we… Addition
- Finally one should add that in spite of the great complexity of protein synthesis and in spite of the considerable technical difficulties in synthesizing polynucleotides… Add
- One can say, looking at the papers in this symposium, that the elucidation of the genetic code is indeed a great achievement. It is, in… Achievement
- Trying to determine the structure of a protein by UV spectroscopy was like trying to determine the structure of a piano by listening to the… Determine
- Our ... advantage was that we had evolved unstated but fruitful methods of collaboration ... If either of us suggested a new idea, the other,… Advantage
- In my experience most mathematicians are intellectually lazy. Experience
- God is a hacker, not an engineer Engineer
- We are sometimes asked what the result would be if we put four +'s in one gene. To answer this my colleagues have recently put… Answer
- This seems highly likely, especially as it has been shown that in several systems mutations affecting the same amino acid are extremely near together on… Acid
- Moreover the incorporation requires the same components needed for protein synthesis, and is inhibited by the same inhibitors. Thus the system is most unlikely to… Artefact
- It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure… Across
- It seems likely that most if not all the genetic information in any organism is carried by nucleic acid - usually by DNA, although certain… Acid
- It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in… Acid
- It now seems certain that the amino acid sequence of any protein is determined by the sequence of bases in some region of a particular… Acid
- It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code is indeed a… Biochemical
- If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt… All
- The meaning of this observation is unclear, but it raises the unfortunate possibility of ambiguous triplets; that is, triplets which may code more than one… Acid
- The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that… Acid
- How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us… Acid
- For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the… Base