“Why had the introduction of a supposedly harmless virus carrying a gene into the liver caused such a devastating, fatal reaction? As physicians, scientists, and regulators sifted through the trial, the reasons for the failed experiment became evident. The vectors… — Siddhartha Mukherjee Copy Share Image
“The cloning of human genes allowed scientists to manufacture proteins-and the synthesis of proteins opened the possibility of targeting the millions of biochemical reactions in the human body. Proteins made it possible for chemists to intervene on previously impenetrable aspects… — Siddhartha Mukherjee Copy Share Image
Most days, I go home and I feel rejuvenated. I feel ebullient. — Siddhartha Mukherjee Copy Share Image
“A note of caution: epigenetics is also on the verge of transforming into a dangerous idea. Epigenetic modifications of genes can potentially superpose historical… — Siddhartha Mukherjee Copy Share Image
When you immerse yourself in medicine you realise that hope is not absolute. It's not that simple. — Siddhartha Mukherjee Copy Share Image
“I had a novice's hunger for history, but also a novice's inability to envision it.” — Siddhartha Mukherjee Copy Share Image
“Any extrapolation of history into the future presupposes an environment of static discovery—an oxymoron.” — Siddhartha Mukherjee Copy Share Image
“Six decades and two years, no more than a passing glance of time, separate Mendel's initial experiments on peas and the court-mandated sterilization of… — Siddhartha Mukherjee Copy Share Image
“We now know that cells have ancient detectors that recognize viral genes and stamp them with chemical marks, like cancellation signs, to prevent their… — Siddhartha Mukherjee Copy Share Image
“Familial schizophrenia (like normal human features such as intelligence and temperament) is thus highly heritable but only moderately inheritable. In other words, genes-hereditary determinants-are… — Siddhartha Mukherjee Copy Share Image
“If you prefer an “academic life” as a retreat from reality, do not go into biology. This field is for a man or woman… — Siddhartha Mukherjee Copy Share Image
“But the pigs--seventy pounds of porcine weight that did not take kindly to weekly endoscopies--did not sprout any ulcers. And testing the theory on… — Siddhartha Mukherjee Copy Share Image
“One of the four genes used by Yamanaka to reverse cellular fate is called c-myc. Myc, the rejuvenating factor, is no ordinary gene: it… — Siddhartha Mukherjee Copy Share Image
A breast cancer might turn out to have a close resemblance to a gastric cancer. And this kind of reorganization of cancer in terms… — Siddhartha Mukherjee Copy Share Image
