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Like antidepressants, a substantial part of the benefit of…

“Like antidepressants, a substantial part of the benefit of psychotherapy depends on a placebo effect, or as Moerman calls it, the meaning response. At least part of the improvement that is produced by these treatments is due to the relationship between the therapist and the client and to the…” quote by Irving Kirsch
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““Like antidepressants, a substantial part of the benefit of psychotherapy depends on a placebo effect, or as Moerman calls it, the meaning response. At least part of the improvement that is produced by these treatments is due to the relationship between the therapist and the client and to the client's expectancy of getting better. That is a problem for antidepressant treatment. It is a problem because drugs are supposed to work because of their chemistry, not because of the psychological factors. But it is not a problem for psychotherapy. Psychotherapists are trained to provide a warm and caring environment in which therapeutic change can take place. Their intention is to replace the hopelessness of depression with a sense of hope and faith in the future. These tasks are part of the essence of psychotherapy. The fact that psychotherapy can mobilize the meaning response - and that it can do so without deception - is one of its strengths, no one of its weaknesses. Because hopelessness is a fundamental characteristic of depression, instilling hope is a specific treatment for it it. Invoking the meaning response is essential for the effective treatment of depression, and the best treatments are those that can do this most effectively and that can do without deception.””

Irving Kirsch

About This Quote

This interpretation was drafted with AI assistance. It is one reading of the quote, not the author's own explanation.

Psychotherapy’s benefit partly comes from patients’ expectations and therapeutic relationship, a “meaning response” similar to placebo but without deception.

In simple terms: Therapy works through hope and meaning, not just chemistry.

Key Takeaway

Leverage therapeutic alliance to foster hope.

Themes

psychotherapy expectancy hope meaning response

Mood

hopeful reflective

Type

clinical educational

When to use this quote

  • clinical sessions
  • patient intake
  • therapy training
  • depression treatment

Key Concepts

placebo effect therapeutic alliance expectancy theory

Questions to Reflect On

  • How can clinicians strengthen the meaning response?
  • What limits the placebo-like benefits in therapy?
A Different Perspective

Effectiveness may vary with therapist skill and patient openness.

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