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A lot of science doesn't require big "ns" but if you're…

“A lot of science doesn't require big "ns" but if you're trying to understand something about human health and you're looking at interventions that are not going to be either killing you or making you live forever - they're going to have some tweaking on the outcome - you need big numbers or you…” quote by Francis Collins
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“A lot of science doesn't require big "ns" but if you're trying to understand something about human health and you're looking at interventions that are not going to be either killing you or making you live forever - they're going to have some tweaking on the outcome - you need big numbers or you don't have enough power.”

Francis Collins

About This Quote

This interpretation was drafted with AI assistance. It is one reading of the quote, not the author's own explanation.

Understanding human health interventions requires large sample sizes to achieve statistical power; small studies may lack reliability.

In simple terms: Big data is needed for reliable health research.

Key Takeaway

Prioritize studies with sufficient sample sizes.

Themes

science health statistics research methodology

Mood

analytical pragmatic cautious

Type

scientific methodological practical

When to use this quote

  • designing clinical trials
  • public health policy
  • epidemiological studies
  • grant proposals
  • data analysis

Key Concepts

statistical power sample size intervention efficacy

Questions to Reflect On

  • What alternatives exist when large samples aren't feasible?
  • How can we improve study design with limited data?
A Different Perspective

Large numbers may be impractical or unethical in some contexts.

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