Impudence is the worst of all human diseases.

Human diseases are the same as they were a thousand years ago, but doctors have given them more expensive names.

— Vikrant Parsai

Fear is the most subtle and destructive of all human diseases.

— Smiley Blanton

First of all, many human diseases are influenced by, if not caused by mutations in genes.

— Daniel Nathans

I hated [Robert Mugabe]. He's one of the worst human beings I've ever met. He treated black and white with equal contempt. He was…

— Bob Hawke

The worst of all human ailments: indecision.

— Napoleon Hill

“His only words were that he regarded cowardice as one of the worst human sins.”

— Mikhail Bulgakov

“let’s not forget, but make it our business to record the worst of the human viciousness we’ve seen without changing one word.”

— Louis-Ferdinand Céline

Art almost always has its ingredient of impudence, its flouting of established authority, so that it may substitute its own authority and its own…

— Ben Shahn

“Do it, my fellow Americans! Do it for every adolescent anomic skank genius cloistered in his room, getting cranked, rabidly humping his sampler as…

— Mark Leyner

Satiation, like any state of vitality, always contains a degree of impudence, and that impudence emerges first and foremost when the sated man instructs…

— Anton Chekhov

Long live impudence. It was my guardian angel in this world.

— Albert Einstein

Folly often goes beyond her bounds, but impudence knows none.

— Ben Jonson

I do not believe that since man was in the habit of living on this planet anyone has ever lived possessed of the impudence…

— Jay Gould

Impertinence will intermeddle in things in which it has no concern, showing a want of breeding, or, more commonly, a spirit of sheer impudence.

— George Crabbe

Want of principle is power. Truth and honesty set a limit to our efforts, which impudence and hypocrisy easily overleap.

— William Hazlitt