David Andrew Sinclair

I actually think it will be possible one day to be immortal.

— David Andrew Sinclair

We once thought of cancer as an incurable disease; then we started treating it.

— David Andrew Sinclair

My grandmother is the black-sheep rebel of the family.

— David Andrew Sinclair

I believe in my work and advocate for my conclusions.

— David Andrew Sinclair

Scientists don't like to be called salesmen.

— David Andrew Sinclair

I was criticized for saying that Pfizer doesn't know how to make a molecule right.

— David Andrew Sinclair

Doctors will prescribe medicines for a particular disease but, as a side effect, those medications will work to prevent dozens of others.

— David Andrew Sinclair

Unfortunately, because aging is so common and natural, we tend to think of it as destiny or something we should accept.

— David Andrew Sinclair

Well, originally we found resveratrol just in a test tube, looking for molecules that would turn on this enzyme, this protein that…

— David Andrew Sinclair

The way to make a worm live longer is probably quite different from making a human live longer.

— David Andrew Sinclair

So aging is really just the way we deteriorate over time. Lifespan on the other hand is how long we live. We…

— David Andrew Sinclair

I tried calorie restriction and couldn't do it. It's really hard to be hungry all the time.

— David Andrew Sinclair

Aging is just like any deterioration of the body. It fulfills every category of what we call a disease except one: it…

— David Andrew Sinclair

I'm driven to get to goals as fast as possible. It frustrates people in my lab who have something they think is…

— David Andrew Sinclair

As we get better at reversing aging it will be possible to take one medicine and within weeks feel and even look…

— David Andrew Sinclair

I thought that tackling aging and the mechanisms that promote life would be worth figuring out. I wanted to learn why it…

— David Andrew Sinclair

The ultimate goal is to have a pill that can prevent or reverse all diseases of aging. The major diseases that I'd…

— David Andrew Sinclair

If I'm not hungry and I'm busy, I am quite happy to skip a meal. It's informal intermittent fasting. I feel strongly…

— David Andrew Sinclair

So what we're all hoping to do, us researchers, is to develop ways to not really just extend lifespan but to keep…

— David Andrew Sinclair

You want to shock the body and not be constant. Intermittent fasting is an increasingly popular way: Skip breakfast, for example. Also…

— David Andrew Sinclair

We used to think that aging was a lot like, as if we were cars made fresh and youthful and then we've…

— David Andrew Sinclair

A lot of scientists are hesitant to get involved with industry. It's seen as, you know, getting in bed with the devil,…

— David Andrew Sinclair

Resveratrol had a decent benefit when the mice were obese and sedentary. The mice that were fed a lean diet and resveratrol…

— David Andrew Sinclair

When I started in the field, aging research was the backwater of biology. The idea that you could find a molecule that…

— David Andrew Sinclair

We can change our lives for the better, and always have. We used to think pain during surgery and dying during childbirth…

— David Andrew Sinclair

Resveratrol does not act primarily as an antioxidant. It is far more interesting and powerful than that. Resveratrol turns on our body's…

— David Andrew Sinclair

The mice that had the resveratrol in their diet were still obese, but they were seemingly or relatively immune to the effects…

— David Andrew Sinclair

We've always known that our bodies are capable of healing themselves under the right conditions: Diet and exercise improve our health. But…

— David Andrew Sinclair

It's been known since 1916 that cutting back calories is beneficial in every organism it's been tested on - from yeast to…

— David Andrew Sinclair

Only 20 percent of our longevity is genetically determined. The rest is what we do, how we live our lives and increasingly…

— David Andrew Sinclair

Well, we can study aging in people, but of course those studies take decades. So what we try to do is we…

— David Andrew Sinclair