““The factor VIII project, both teams knew, would challenge the outer limits of gene-cloning technology. Somatostatin had 14 amino acids; insulin had 51. Factor VIII had 2,350. The leap in size between somatostatin and factor VIII was 160-fold-almost equivalent to the jump in distance between Wilbur Wright's first airborne circle at Kitty Hawk and Lindbergh's journey across the Atlantic.””
