““It is fiercely inventive. It squeezes complexity out of simplicity. It orchestrates the activation or repression of certain genes in only certain cells and at certain times, creating unique contexts and partners for each gene in time and space, and thus produces near-infinite functional variation out of its limited repertoire. And it mixes and matches gene modules-called exons-within single genes to extract even further combinatorial diversity out of its gene repertoire. These two strategies-gene regulation and gene splicing-appear to be used more extensively in the human genome than in the genomes of most organisms. More than the enormity of gene numbers, the diversity of gene types, or the originality of gene function, it is the ingenuity of our genome that is the secret to our complexity.””
