““we proposed eighteen great ideas of science that we felt framed virtually all discoveries of the natural world and all advances in technology. We could not have foreseen many of the remarkable developments of the past two decades—nanotechnology archaea, LEDs, cloning, dark energy, ancient microbial fossils and deep microbial life, evidence for oceans of water on Mars and lakes of methane on Titan, ribozymes, carbon nanotubes, extrasolar planets, and so much more. But all of these unanticipated findings fit into the existing framework of science. The core concepts of science have not changed, and we are unable to point to any fundamentally new scientific principle that has emerged during the 1990s or 2000s. Accordingly, while every chapter has been significantly updated, we have added only a single new chapter on the explosion of advances in biotechnology. We conclude that the experience of the past two decades underscores the value of the great ideas approach to achieving scientific literacy.””