Cool Quote by Jacques Dubochet
“It would be great if you could cool the water and immobilise the molecules, though keeping the structure, because when it's frozen, when it's immobilised, you can have it in the electron microscope and the water will not evaporate because in the electron microscope, it must be under vacuum, and water at normal temperature evaporates.”
About This Quote
Source Scientific Lecture: Cryo‑EM conference, 2013
Cooling water while preserving its structure enables electron microscopy without evaporation.
In simple terms: Freeze water to view it under a microscope.
Key Takeaway
Preserve samples by rapid freezing.
Themes
science
technology
microscopy
Mood
technical
curious
Type
explanatory
informative
When to use this quote
- biological imaging
- structural biology
- nanotechnology
- materials science
Key Concepts
Cryogenics
electron microscopy
sample preservation
Questions to Reflect On
- What samples benefit most from cryo‑EM?
- How does freezing affect molecular integrity?
A Different Perspective
Freezing may alter delicate structures; not all samples survive.
