Biggest Quote by Anne Wojcicki
“I think the biggest problem in clinical trials is that they are underpowered. And that fundamentally, the studies are just too small.”
About This Quote
Clinical trials often lack sufficient participants, leading to weak statistical power and unreliable results.
In simple terms: Small studies give weak conclusions.
Key Takeaway
Ensure adequate sample size.
Themes
research methodology
statistics
healthcare
Mood
analytical
pragmatic
Type
scientific
strategic
When to use this quote
- drug development
- medical research
- policy planning
- grant proposals
Key Concepts
statistical power
sample size determination
Questions to Reflect On
- What strategies can improve trial enrollment?
- How to balance cost with statistical needs?
A Different Perspective
Increasing size raises cost and logistical complexity.
![“A review of seventy-four clinical trials of antidepressants, for example, found that thirty-seven of thirty-eight positive studies [that praised the drugs] were published. But of the thirty-six negative studies, thirty-three were either not published or published in a form that conveyed a positive…” quote by Marcia Angell](https://sms4smile.com/quotes/img-quotes/1cb/marcia-angell-19102_antidepressants_a-review-of-seventy-four-clinical-trials_2205018.jpg)
![“When a drug comes out [that's broadly prescribed] there are going to start to be a lot of people on it [in a million person cohort] and you might get therefore an early signal of something unexpected that hadn't come through in the clinical trials. And I'm sure [drug companies] would love it if…” quote by Francis Collins](https://sms4smile.com/quotes/img-quotes/dda/francis-collins-5281_able_when-a-drug-comes-out-that-s-broadly-pre_408526.jpg)
