“In 1962, Watson, Crick, and Wilkins won the Nobel Prize for their discovery. Franklin was not included in the prize. She had died in 1958, at the age of thirty-seven, from diffusely metastatic ovarian cancer-an illness ultimately linked to mutations in genes.” — Siddhartha Mukherjee Copy Share Image
“Aristotle was wrong in his partitioning of male and female contributions into "material" and "message," but abstractly, he had captured one of the essential truths about the nature of heredity. The transmission of heredity, as Aristotle perceived it, was essentially… — Siddhartha Mukherjee Copy Share Image
“A note of caution: epigenetics is also on the verge of transforming into a dangerous idea. Epigenetic modifications of genes can potentially superpose historical… — Siddhartha Mukherjee Copy Share
When you immerse yourself in medicine you realise that hope is not absolute. It's not that simple. — Siddhartha Mukherjee Copy Share
“I had a novice's hunger for history, but also a novice's inability to envision it.” — Siddhartha Mukherjee Copy Share
“Any extrapolation of history into the future presupposes an environment of static discovery—an oxymoron.” — Siddhartha Mukherjee Copy Share
“Six decades and two years, no more than a passing glance of time, separate Mendel's initial experiments on peas and the court-mandated sterilization of… — Siddhartha Mukherjee Copy Share
“We now know that cells have ancient detectors that recognize viral genes and stamp them with chemical marks, like cancellation signs, to prevent their… — Siddhartha Mukherjee Copy Share
“Familial schizophrenia (like normal human features such as intelligence and temperament) is thus highly heritable but only moderately inheritable. In other words, genes-hereditary determinants-are… — Siddhartha Mukherjee Copy Share
“If you prefer an “academic life” as a retreat from reality, do not go into biology. This field is for a man or woman… — Siddhartha Mukherjee Copy Share
“But the pigs--seventy pounds of porcine weight that did not take kindly to weekly endoscopies--did not sprout any ulcers. And testing the theory on… — Siddhartha Mukherjee Copy Share
“One of the four genes used by Yamanaka to reverse cellular fate is called c-myc. Myc, the rejuvenating factor, is no ordinary gene: it… — Siddhartha Mukherjee Copy Share
A breast cancer might turn out to have a close resemblance to a gastric cancer. And this kind of reorganization of cancer in terms… — Siddhartha Mukherjee Copy Share
“But in 1960, oncology was not yet ready for this proposal. Not until several years later did it strike the board that had fired… — Siddhartha Mukherjee Copy Share
“Mutants are necessary to maintain the essence of our selves. Our genomes has negotiated a fragile balance between counterpoised forces, pairing strand with opposite… — Siddhartha Mukherjee Copy Share
“Even an ancient monster needs a name. To name an illness is to describe a certain condition of suffering—a literary act before it becomes… — Siddhartha Mukherjee Copy Share
