“The tightness of genetic linkage, in short, was a surrogate for the physical proximity of genes on chromosomes: by measuring how often two features-blond-hairedness and blue-eyedness-were linked or unlinked, you could measure the distance between their genes on the chromosome.” — Siddhartha Mukherjee Copy Share Image
“The gene responsible for creating white eyes (called white eyed), for instance, was inescapably linked to maleness: no matter how Morgan crossed his flies, only males were born with white eyes. Similarly, the gene for sable color was linked with… — Siddhartha Mukherjee Copy Share Image
Most days, I go home and I feel rejuvenated. I feel ebullient. — Siddhartha Mukherjee Copy Share Image
“A note of caution: epigenetics is also on the verge of transforming into a dangerous idea. Epigenetic modifications of genes can potentially superpose historical… — Siddhartha Mukherjee Copy Share Image
When you immerse yourself in medicine you realise that hope is not absolute. It's not that simple. — Siddhartha Mukherjee Copy Share Image
“I had a novice's hunger for history, but also a novice's inability to envision it.” — Siddhartha Mukherjee Copy Share Image
“Any extrapolation of history into the future presupposes an environment of static discovery—an oxymoron.” — Siddhartha Mukherjee Copy Share Image
“Six decades and two years, no more than a passing glance of time, separate Mendel's initial experiments on peas and the court-mandated sterilization of… — Siddhartha Mukherjee Copy Share Image
“We now know that cells have ancient detectors that recognize viral genes and stamp them with chemical marks, like cancellation signs, to prevent their… — Siddhartha Mukherjee Copy Share Image
“Familial schizophrenia (like normal human features such as intelligence and temperament) is thus highly heritable but only moderately inheritable. In other words, genes-hereditary determinants-are… — Siddhartha Mukherjee Copy Share Image
“If you prefer an “academic life” as a retreat from reality, do not go into biology. This field is for a man or woman… — Siddhartha Mukherjee Copy Share Image
“But the pigs--seventy pounds of porcine weight that did not take kindly to weekly endoscopies--did not sprout any ulcers. And testing the theory on… — Siddhartha Mukherjee Copy Share Image
“One of the four genes used by Yamanaka to reverse cellular fate is called c-myc. Myc, the rejuvenating factor, is no ordinary gene: it… — Siddhartha Mukherjee Copy Share Image
A breast cancer might turn out to have a close resemblance to a gastric cancer. And this kind of reorganization of cancer in terms… — Siddhartha Mukherjee Copy Share Image
