“Most commonly, hypertensive emergencies occur in the setting of uncontrolled or unknown chronic hypertension. Hypertensive emergencies also may develop as secondary hypertension in association with such diverse etiologies as renal vascular disease, sleep apnea, hyperaldosteronism, pheochromocytoma, and pregnancy (preeclampsia).” — Jean-Louis Vincent Copy Share Image
“These vascular changes, evident to the clinician by examination of the retina, are mirrored by changes in the kidney, leading to a proliferative arteritis,… — Jean-Louis Vincent Copy Share
“7 Severe hemophagocytic syndrome with failure of one or more organs. The choice of cytoreductive regimen depends on the type of malignancy, which is… — Jean-Louis Vincent Copy Share
“Nicardipine is metabolized by the liver, and excretion can be impaired in patients with abnormal hepatic function.” — Jean-Louis Vincent Copy Share
“Most commonly, hypertensive emergencies occur in the setting of uncontrolled or unknown chronic hypertension. Hypertensive emergencies also may develop as secondary hypertension in association… — Jean-Louis Vincent Copy Share
“Newer agents for treatment of seizures in critically ill patients include the phenytoin prodrug, fosphenytoin; the anesthetic agent, propofol; and the water-soluble benzodiazepine, midazolam.” — Jean-Louis Vincent Copy Share
“The relationship between BP and mortality in patients with stroke may be “U-shaped.” According to this notion, systolic BP (SBP) values above or below… — Jean-Louis Vincent Copy Share
“Although specific treatments for ALI/ARDS have been slow to emerge, the recent development of new strategies for mechanical ventilation that improve mortality, and fluid… — Jean-Louis Vincent Copy Share
“Acute pain is triggered by stimulation of peripheral nociceptors in the skin or deeper structures and is a complex process involving multiple mediators at… — Jean-Louis Vincent Copy Share
“On the basis of a recent meta-analysis,25,26 continuous peripheral analgesic techniques provide superior analgesia, reduce opioid consumption, and reduce opioid-related side effects (nausea and… — Jean-Louis Vincent Copy Share
“Several sedation scales—the Richmond Agitation Sedation Scale (RASS), Adaptation to the Intensive Care Environment (ATICE) tool, and the Minnesota Sedation Assessment Tool (MSAT)—as well… — Jean-Louis Vincent Copy Share
“Whenever possible, at least 10 to 15 mL of blood should be withdrawn and inoculated into 2 or 3 bottles or tubes at a ratio… — Jean-Louis Vincent Copy Share
“These effects result in depletion of cellular adenosine triphosphate (ATP) and potentially severe detrimental effects on cell function. It is important to note that… — Jean-Louis Vincent Copy Share
“Febrile patients with head trauma, subarachnoid hemorrhage, or stroke should receive antipyretics to prevent temperature-related increases in cerebral oxygen utilization.” — Jean-Louis Vincent Copy Share
“VIP rule Ventilate: give oxygen therapy, endotracheal intubation if required. Infuse: give IV fluids. Pump: use vasoactive agents first to raise arterial pressure if… — Jean-Louis Vincent Copy Share
“Some physiologic responses to acute pain and stress are mediated by neuroendocrine activation and increased sympathetic tone. As a consequence, patients develop tachycardia, increased… — Jean-Louis Vincent Copy Share