--- title: "Meaning & Key Takeaway of: It is also reasonable to speculate that…" description: "\"“It is also reasonable to speculate that the capacity of prophages to be induced at a low frequency must in itself be advantageous to the phage genome...." image: "https://sms4smile.com/quotes/i/7db/michael-g-cordingley-38351_hedging_it-is-also-reasonable-to-speculate-that_550409.jpg" --- # It is also reasonable to speculate that the capacity of… ![“It is also reasonable to speculate that the capacity of prophages to be induced at a low frequency must in itself be advantageous to the phage genome. It is attractive to think of this as a hedging strategy, in which the genetically identical phage population can simultaneously exploit two…” quote by Michael G Cordingley](https://sms4smile.com/quotes/i/7db/michael-g-cordingley-38351_hedging_it-is-also-reasonable-to-speculate-that_550409.jpg) [Download](https://sms4smile.com/quotes/i/7db/michael-g-cordingley-38351_hedging_it-is-also-reasonable-to-speculate-that_550409.jpg) [Open image](https://sms4smile.com/quotes/i/7db/michael-g-cordingley-38351_hedging_it-is-also-reasonable-to-speculate-that_550409.jpg) > ““It is also reasonable to speculate that the capacity of prophages to be induced at a low frequency must in itself be advantageous to the phage genome. It is attractive to think of this as a hedging strategy, in which the genetically identical phage population can simultaneously exploit two different phenotypes - in this case, to optimize its probability of genetic success. Lysogeny can be considered as phage conservatism, a strategy suited to survival in adverse conditions, Lytic replication is high-stakes gambling that pays off with confident prediction of outcomes. A phage that never takes advantage of the rewards of the high-stakes game (except under dire and uncertain circumstances) will not be as evolutionary successful as the generally conservative phage with an occasionally successful flutter that, rewards with a burst of more rapid amplification. It seems likely then that phages have evolved to spontaneously induce, in a stochastic manner, in order to take advantage of lytic replication while not jeopardizing the genetically identical population of prophages still languishing in the chromosones of their slowly dividing hosts.”” [Michael G Cordingley](https://sms4smile.com/quotes/author/michael-g-cordingley/) ## About This Quote This interpretation was drafted with AI assistance. It is one reading of the quote, not the author's own explanation. Phages use a mixed strategy of low‑frequency induction and stable lysogeny to balance risk and reward, enhancing survival. **In simple terms:** Phages hedge bets between safe and risky replication. Key Takeaway Balance risk with stability. Themes evolution risk management biology Mood analytical speculative Type theoretical educational When to use this quote - research planning - risk assessment - resource allocation Key Concepts stochastic processes viral strategies Questions to Reflect On - What conditions favor lysogeny over lysis? - How can this hedging concept apply to human decision‑making? A Different Perspective May oversimplify complex host‑phage dynamics. ★ ★ ★ ★ ★ No ratings yet [Hedging](https://sms4smile.com/quotes/about/hedging/) ## Related quotes > [You should avoid hedging, at least that's what I think. You should be ashamed to die until you've made some contribution to mankind.](https://sms4smile.com/quotes/vernon-johns/you-should-avoid-hedging-at-least-that-s-what-i-think-you-should-be/) Vernon Johns > [As value investors, our business is to buy bargains that financial market theory says do not exist. We've delivered great returns to our clients…](https://sms4smile.com/quotes/seth-klarman/as-value-investors-our-business-is-to-buy-bargains-that-financial/) [Seth Klarman](https://sms4smile.com/quotes/author/seth-klarman/) > [ \[Donald Trump\] hedging his bets because he's used to buying politicians. ](https://sms4smile.com/quotes/marco-rubio/donald-trump-hedging-his-bets-because-he-s-used-to-buying-politicians/) [Marco Rubio](https://sms4smile.com/quotes/author/marco-rubio/) > [I don't really like hedging. To me, if something needs to be hedged, you shouldn't have a position in it.](https://sms4smile.com/quotes/stanley-druckenmiller/i-don-t-really-like-hedging-to-me-if-something-needs-to-be-hedged-you/) [Stanley Druckenmiller](https://sms4smile.com/quotes/author/stanley-druckenmiller/) > [We concluded that you cannot rely on delta hedging alone. It sounds simplistic to say that now, but back then, this was the sort…](https://sms4smile.com/quotes/john-hull/we-concluded-that-you-cannot-rely-on-delta-hedging-alone-it-sounds/) [John Hull](https://sms4smile.com/quotes/author/john-hull/) > [My second Christian name is John. Good solid bourgeois Christian name, like my first name, Peter, a rock. Minerals. Build on rock, rocks, uranium.…](https://sms4smile.com/quotes/peter-greenaway/my-second-christian-name-is-john-good-solid-bourgeois-christian-name/) [Peter Greenaway](https://sms4smile.com/quotes/author/peter-greenaway/) > [So, in a way I was hedging and saying that if the Olympic stuff doesn't work out at least I can be a lawyer.](https://sms4smile.com/quotes/frank-shorter/so-in-a-way-i-was-hedging-and-saying-that-if-the-olympic-stuff-doesn/) [Frank Shorter](https://sms4smile.com/quotes/author/frank-shorter/) > [“Life is so diversified that to any statement I could make about living organisms there are exceptions. Because of the many exceptions, I should…](https://sms4smile.com/quotes/lee-spetner/life-is-so-diversified-that-to-any-statement-i-could-make-about/) [Lee Spetner](https://sms4smile.com/quotes/author/lee-spetner/) > [This was not some pretty little girl, coyly flirtatious, delicately stimulated. This was the mature female of the species, vivid, handsome and strong demanding…](https://sms4smile.com/quotes/john-d-macdonald/this-was-not-some-pretty-little-girl-coyly-flirtatious-delicately/) [John D. MacDonald](https://sms4smile.com/quotes/author/john-d-macdonald/) > [“Are you hungry?" he asks, hedging. "I don't have to be." "What does that even mean, Mia? ”](https://sms4smile.com/quotes/christina-lauren/are-you-hungry-he-asks-hedging-i-don-t-have-to-be-what-does-that-even/) [Christina Lauren](https://sms4smile.com/quotes/author/christina-lauren/) > [“The only occasional gripe was about the volatile price of Bitcoin, which made it hard to know how much a vendor would be charging…](https://sms4smile.com/quotes/nathaniel-popper/the-only-occasional-gripe-was-about-the-volatile-price-of-bitcoin/) [Nathaniel Popper](https://sms4smile.com/quotes/author/nathaniel-popper/) > [“Hedging is expensive and dilutes commitment.”](https://sms4smile.com/quotes/andrew-s-grove/hedging-is-expensive-and-dilutes-commitment/) [Andrew S. Grove](https://sms4smile.com/quotes/author/andrew-s-grove/) > [They (the youth of Australia) are out there clamouring in all forms of voice, and they are not so much hedging us older Australians…](https://sms4smile.com/quotes/peter-cosgrove/they-the-youth-of-australia-are-out-there-clamouring-in-all-forms-of/) [Peter Cosgrove](https://sms4smile.com/quotes/author/peter-cosgrove/) > [I was hedging my bets by the time I got to college. I was interested in drama and journalism and psychology.](https://sms4smile.com/quotes/hank-azaria/i-was-hedging-my-bets-by-the-time-i-got-to-college-i-was-interested/) [Hank Azaria](https://sms4smile.com/quotes/author/hank-azaria/) > [If the guy out in the woods with the Michigan Militia is a real estate negotiator, instead of some crackpot, and has a normal…](https://sms4smile.com/quotes/michael-moore/if-the-guy-out-in-the-woods-with-the-michigan-militia-is-a-real/) [Michael Moore](https://sms4smile.com/quotes/author/michael-moore/) ## More by Michael G Cordingley > [“ERV envelope genes possess unique properties that make them suitable for use in forming the placenta: they are fusogenic proteins and they have immunosuppresive…](https://sms4smile.com/quotes/michael-g-cordingley/erv-envelope-genes-possess-unique-properties-that-make-them-suitable/) [Michael G Cordingley](https://sms4smile.com/quotes/author/michael-g-cordingley/) > [“In early primates, we can pinpoint a particular ERV integration event into the locus of the pancreatic amylase gene that conferred upon our ancestors…](https://sms4smile.com/quotes/michael-g-cordingley/in-early-primates-we-can-pinpoint-a-particular-erv-integration-event/) [Michael G Cordingley](https://sms4smile.com/quotes/author/michael-g-cordingley/) > [“Such then is the nature of quasispecies : the density of the sequence cloud at any point in sequence space is determined by the…](https://sms4smile.com/quotes/michael-g-cordingley/such-then-is-the-nature-of-quasispecies-the-density-of-the-sequence/) [Michael G Cordingley](https://sms4smile.com/quotes/author/michael-g-cordingley/) > [“The litter of ERVs across vertebrate genomes, mainly in the form of defective and deleted proviruses, mutationally inactivated proteins coding sequences, and isolated LTRs,…](https://sms4smile.com/quotes/michael-g-cordingley/the-litter-of-ervs-across-vertebrate-genomes-mainly-in-the-form-of/) [Michael G Cordingley](https://sms4smile.com/quotes/author/michael-g-cordingley/) > [“The results of the studies opened up a whole new avenue of research into live-attenuated vaccines: synthetic attenuated virus engineering (SAVE). A virus was…](https://sms4smile.com/quotes/michael-g-cordingley/the-results-of-the-studies-opened-up-a-whole-new-avenue-of-research/) [Michael G Cordingley](https://sms4smile.com/quotes/author/michael-g-cordingley/) > [“Unlike lytic phages, CTXφ can actively replicate within V. cholerae and generate progeny phages without killing its host cell. The process of phage induction…](https://sms4smile.com/quotes/michael-g-cordingley/unlike-lytic-phages-ctx-can-actively-replicate-within-v-cholerae-and/) [Michael G Cordingley](https://sms4smile.com/quotes/author/michael-g-cordingley/) > [“The researchers looked deeper into these observations, in hopes of gaining insight into the mechanisms underlying the high evolutionary rate and extraordinary immunologic plasticity…](https://sms4smile.com/quotes/michael-g-cordingley/the-researchers-looked-deeper-into-these-observations-in-hopes-of/) [Michael G Cordingley](https://sms4smile.com/quotes/author/michael-g-cordingley/) > [“The accelerating pace of zoonotic transmission of novel viruses into humans is attributable to anthropogenic epidemiologic factors. Only behavior modification or medical management of…](https://sms4smile.com/quotes/michael-g-cordingley/the-accelerating-pace-of-zoonotic-transmission-of-novel-viruses-into/) [Michael G Cordingley](https://sms4smile.com/quotes/author/michael-g-cordingley/) > [“The basis for the potential of all virolytic therapeutics resides in the exquisite selectivity they exhibit for infecting and killing cancer cells. The very…](https://sms4smile.com/quotes/michael-g-cordingley/the-basis-for-the-potential-of-all-virolytic-therapeutics-resides-in/) [Michael G Cordingley](https://sms4smile.com/quotes/author/michael-g-cordingley/) > [“Vaccination with a live-attenuated virus vaccine can be compared with the cross-species transmission of viruses that cause zoonotic infection. If the vaccine strain is…](https://sms4smile.com/quotes/michael-g-cordingley/vaccination-with-a-live-attenuated-virus-vaccine-can-be-compared-with/) [Michael G Cordingley](https://sms4smile.com/quotes/author/michael-g-cordingley/) > [“Collectively, the veritable zoo of mobile genetic elements comprises a remarkable 40 percent of our genome. The retroviral sequences littered across all vertebrate genomes…](https://sms4smile.com/quotes/michael-g-cordingley/collectively-the-veritable-zoo-of-mobile-genetic-elements-comprises-a/) [Michael G Cordingley](https://sms4smile.com/quotes/author/michael-g-cordingley/) [Explore all 12 Michael G Cordingley quotes ](https://sms4smile.com/quotes/author/michael-g-cordingley/) ## More Hedging quotes > [You should avoid hedging, at least that's what I think. You should be ashamed to die until you've made some contribution to mankind.](https://sms4smile.com/quotes/vernon-johns/you-should-avoid-hedging-at-least-that-s-what-i-think-you-should-be/) Vernon Johns > [I was hedging my bets by the time I got to college. I was interested in drama and journalism and psychology.](https://sms4smile.com/quotes/hank-azaria/i-was-hedging-my-bets-by-the-time-i-got-to-college-i-was-interested/) [Hank Azaria](https://sms4smile.com/quotes/author/hank-azaria/) > [They (the youth of Australia) are out there clamouring in all forms of voice, and they are not so much hedging us older Australians…](https://sms4smile.com/quotes/peter-cosgrove/they-the-youth-of-australia-are-out-there-clamouring-in-all-forms-of/) [Peter Cosgrove](https://sms4smile.com/quotes/author/peter-cosgrove/) > [“Hedging is expensive and dilutes commitment.”](https://sms4smile.com/quotes/andrew-s-grove/hedging-is-expensive-and-dilutes-commitment/) [Andrew S. Grove](https://sms4smile.com/quotes/author/andrew-s-grove/) > [“The only occasional gripe was about the volatile price of Bitcoin, which made it hard to know how much a vendor would be charging…](https://sms4smile.com/quotes/nathaniel-popper/the-only-occasional-gripe-was-about-the-volatile-price-of-bitcoin/) [Nathaniel Popper](https://sms4smile.com/quotes/author/nathaniel-popper/) > [“Are you hungry?" he asks, hedging. "I don't have to be." "What does that even mean, Mia? ”](https://sms4smile.com/quotes/christina-lauren/are-you-hungry-he-asks-hedging-i-don-t-have-to-be-what-does-that-even/) [Christina Lauren](https://sms4smile.com/quotes/author/christina-lauren/) > [This was not some pretty little girl, coyly flirtatious, delicately stimulated. This was the mature female of the species, vivid, handsome and strong demanding…](https://sms4smile.com/quotes/john-d-macdonald/this-was-not-some-pretty-little-girl-coyly-flirtatious-delicately/) [John D. MacDonald](https://sms4smile.com/quotes/author/john-d-macdonald/) > [“Life is so diversified that to any statement I could make about living organisms there are exceptions. Because of the many exceptions, I should…](https://sms4smile.com/quotes/lee-spetner/life-is-so-diversified-that-to-any-statement-i-could-make-about/) [Lee Spetner](https://sms4smile.com/quotes/author/lee-spetner/) > [So, in a way I was hedging and saying that if the Olympic stuff doesn't work out at least I can be a lawyer.](https://sms4smile.com/quotes/frank-shorter/so-in-a-way-i-was-hedging-and-saying-that-if-the-olympic-stuff-doesn/) [Frank Shorter](https://sms4smile.com/quotes/author/frank-shorter/) > [My second Christian name is John. Good solid bourgeois Christian name, like my first name, Peter, a rock. Minerals. Build on rock, rocks, uranium.…](https://sms4smile.com/quotes/peter-greenaway/my-second-christian-name-is-john-good-solid-bourgeois-christian-name/) [Peter Greenaway](https://sms4smile.com/quotes/author/peter-greenaway/) > [We concluded that you cannot rely on delta hedging alone. It sounds simplistic to say that now, but back then, this was the sort…](https://sms4smile.com/quotes/john-hull/we-concluded-that-you-cannot-rely-on-delta-hedging-alone-it-sounds/) [John Hull](https://sms4smile.com/quotes/author/john-hull/) > [I don't really like hedging. To me, if something needs to be hedged, you shouldn't have a position in it.](https://sms4smile.com/quotes/stanley-druckenmiller/i-don-t-really-like-hedging-to-me-if-something-needs-to-be-hedged-you/) [Stanley Druckenmiller](https://sms4smile.com/quotes/author/stanley-druckenmiller/) > [ \[Donald Trump\] hedging his bets because he's used to buying politicians. ](https://sms4smile.com/quotes/marco-rubio/donald-trump-hedging-his-bets-because-he-s-used-to-buying-politicians/) [Marco Rubio](https://sms4smile.com/quotes/author/marco-rubio/) > [As value investors, our business is to buy bargains that financial market theory says do not exist. We've delivered great returns to our clients…](https://sms4smile.com/quotes/seth-klarman/as-value-investors-our-business-is-to-buy-bargains-that-financial/) [Seth Klarman](https://sms4smile.com/quotes/author/seth-klarman/) > [If the guy out in the woods with the Michigan Militia is a real estate negotiator, instead of some crackpot, and has a normal…](https://sms4smile.com/quotes/michael-moore/if-the-guy-out-in-the-woods-with-the-michigan-militia-is-a-real/) [Michael Moore](https://sms4smile.com/quotes/author/michael-moore/) [Browse all 20 Hedging quotes ](https://sms4smile.com/quotes/about/hedging/) ```json { "@context": "https://schema.org", "@graph": [ { "@type": "Quotation", "text": "“It is also reasonable to speculate that the capacity of prophages to be induced at a low frequency must in itself be advantageous to the phage genome. 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