--- title: "Meaning & Key Takeaway of: Consider the clinicaltrials by which…" description: "\"Consider the clinicaltrials by which drugs are tested in human subjects.5 Before a new drug can enter the market, its manufacturer must sponsor clinica..." image: "https://sms4smile.com/quotes/i/ba8/marcia-angell-19102_administration_consider-the-clinicaltrials-by-which-dru_3153044.jpg" --- # Consider the clinicaltrials by which drugs are tested in… ![“Consider the clinicaltrials by which drugs are tested in human subjects.5 Before a new drug can enter the market, its manufacturer must sponsor clinicaltrials to show the Food and Drug Administration that the drug is safe and effective, usually as compared with a placebo or dummy pill. The results…” quote by Marcia Angell](https://sms4smile.com/quotes/i/ba8/marcia-angell-19102_administration_consider-the-clinicaltrials-by-which-dru_3153044.jpg) [Download](https://sms4smile.com/quotes/i/ba8/marcia-angell-19102_administration_consider-the-clinicaltrials-by-which-dru_3153044.jpg) [Open image](https://sms4smile.com/quotes/i/ba8/marcia-angell-19102_administration_consider-the-clinicaltrials-by-which-dru_3153044.jpg) > “Consider the clinicaltrials by which drugs are tested in human subjects.5 Before a new drug can enter the market, its manufacturer must sponsor clinicaltrials to show the Food and Drug Administration that the drug is safe and effective, usually as compared with a placebo or dummy pill. The results of all the trials (there may be many) are submitted to the FDA, and if one or two trials are positive—that is, they show effectiveness without serious risk—the drug is usually approved, even if all the other trials are negative.” [Marcia Angell](https://sms4smile.com/quotes/author/marcia-angell/) ## About This Quote This interpretation was drafted with AI assistance. It is one reading of the quote, not the author's own explanation. Regulatory approval often relies on a few positive trials, overlooking many negative results, which can mislead about a drug’s true safety and efficacy. **In simple terms:** Drugs may be approved despite many failed tests. Key Takeaway Demand more comprehensive evidence before approval. Themes medical ethics regulation pharmaceuticals Mood cautious critical Type analytical informative When to use this quote - healthcare decision making - patient safety - drug development - regulatory review Key Concepts clinical trial bias risk assessment policy Questions to Reflect On - How can regulators ensure balanced evaluation? - What safeguards protect patients from insufficient data? A Different Perspective A single positive result may not reflect overall drug performance. ★ ★ ★ ★ ★ No ratings yet [Administration](https://sms4smile.com/quotes/about/administration/) [Drug](https://sms4smile.com/quotes/about/drug/) [Effectiveness](https://sms4smile.com/quotes/about/effectiveness/) [Fda](https://sms4smile.com/quotes/about/fda/) [Humans](https://sms4smile.com/quotes/about/humans/) [Placebo](https://sms4smile.com/quotes/about/placebo/) [Risk](https://sms4smile.com/quotes/about/risk/) [Trials](https://sms4smile.com/quotes/about/trials/) ## Related quotes > [“Recognize that your attention is the most valuable thing you can ever own, and you alone have the ultimate power to choose where to…](https://sms4smile.com/quotes/sol-luckman/recognize-that-your-attention-is-the-most-valuable-thing-you-can-ever/) [Sol Luckman](https://sms4smile.com/quotes/author/sol-luckman/) > [“Time is a placebo medication, it only helps you if you believe it can, it only heals you if you let it.”](https://sms4smile.com/quotes/cody-edward-lee-miller/time-is-a-placebo-medication-it-only-helps-you-if-you-believe-it-can/) [Cody Edward Lee Miller](https://sms4smile.com/quotes/author/cody-edward-lee-miller/) > [“The gun, my young friend, is that dark cousin of the placebo, the nocebo. 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It means that taking action--no matter what the action is--might help you feel better.](https://sms4smile.com/quotes/anonymous/i-find-placebos-uplifting-and-exhilarating-it-means-that-taking/) [Anonymous](https://sms4smile.com/quotes/author/anonymous/) > [Eventually it became clear that our emotions, attitudes, and thoughts profoundly affect our bodies, sometimes to the degree of life or death. Soon mind-body…](https://sms4smile.com/quotes/larry-dossey/eventually-it-became-clear-that-our-emotions-attitudes-and-thoughts/) [Larry Dossey](https://sms4smile.com/quotes/author/larry-dossey/) > [A man doesn't need a study to know if he's feeling amorous. 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That happens in much of the rest of the health…](https://sms4smile.com/quotes/marcia-angell/the-pharmaceutical-industry-isn-t-the-only-place-where-there-s-waste/) [Marcia Angell](https://sms4smile.com/quotes/author/marcia-angell/) > [ The use of psychoactive drugs - including both antidepressants and antipsychotics - has exploded...\[yet\] 'the tally of those who are disabled...increased nearly two and… ](https://sms4smile.com/quotes/marcia-angell/the-use-of-psychoactive-drugs-including-both-antidepressants-and/) [Marcia Angell](https://sms4smile.com/quotes/author/marcia-angell/) > [Drug companies say they need to charge ever-higher prices to cover their research costs, but they spend far less on research and development than…](https://sms4smile.com/quotes/marcia-angell/drug-companies-say-they-need-to-charge-ever-higher-prices-to-cover/) [Marcia Angell](https://sms4smile.com/quotes/author/marcia-angell/) > [It is simply no longer possible to believe much of the clinical research that is published, or to rely on the judgment of trusted…](https://sms4smile.com/quotes/marcia-angell/it-is-simply-no-longer-possible-to-believe-much-of-the-clinical/) [Marcia Angell](https://sms4smile.com/quotes/author/marcia-angell/) > [It is time for the scientific community to stop giving alternative medicine a free ride There cannot be two kinds of medicine — conventional…](https://sms4smile.com/quotes/marcia-angell/it-is-time-for-the-scientific-community-to-stop-giving-alternative/) [Marcia Angell](https://sms4smile.com/quotes/author/marcia-angell/) > [There is something so biologically implausible that your attitude is going to cure a disease. 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