--- title: "Meaning & Key Takeaway of: We already have intriguing evidence that…" description: "\"“We already have intriguing evidence that some types of chronic pain work by prediction. Animals who have stress or injury early in life become more li..." image: "https://sms4smile.com/quotes/i/e19/lisa-feldman-barrett-18384_chronic-pain_we-already-have-intriguing-evidence-that_551932.jpg" --- # We already have intriguing evidence that some types of… ![“We already have intriguing evidence that some types of chronic pain work by prediction. Animals who have stress or injury early in life become more likely to develop persistent pain. Human infants who have surgery are more likely to have heightened pain in later childhood. (Incredibly, infants…” quote by Lisa Feldman Barrett](https://sms4smile.com/quotes/i/e19/lisa-feldman-barrett-18384_chronic-pain_we-already-have-intriguing-evidence-that_551932.jpg) [Download](https://sms4smile.com/quotes/i/e19/lisa-feldman-barrett-18384_chronic-pain_we-already-have-intriguing-evidence-that_551932.jpg) [Open image](https://sms4smile.com/quotes/i/e19/lisa-feldman-barrett-18384_chronic-pain_we-already-have-intriguing-evidence-that_551932.jpg) > ““We already have intriguing evidence that some types of chronic pain work by prediction. Animals who have stress or injury early in life become more likely to develop persistent pain. Human infants who have surgery are more likely to have heightened pain in later childhood. (Incredibly, infants prior to the 1980s were routinely not anesthetized during major surgery, on the belief that they couldn’t feel pain!)”” [Lisa Feldman Barrett](https://sms4smile.com/quotes/author/lisa-feldman-barrett/) ## About This Quote This interpretation was drafted with AI assistance. It is one reading of the quote, not the author's own explanation. Highlights that chronic pain can be shaped by early stress and predictive brain mechanisms, linking early experiences to later pain sensitivity. **In simple terms:** Early stress predicts later pain. Key Takeaway Consider early life impacts on health. Themes pain neuroscience development prediction Mood informative scientific Type educational When to use this quote - pediatric surgery - mental health counseling - pain management programs Key Concepts predictive coding neuroplasticity early adversity Questions to Reflect On - How can early interventions reduce chronic pain? - What role does expectation play in pain? A Different Perspective Pain perception is also influenced by genetics and environment. ★ ★ ★ ★ ★ No ratings yet [Chronic pain](https://sms4smile.com/quotes/about/chronic-pain/) [Pain](https://sms4smile.com/quotes/about/pain/) ## Related quotes > [“A common misconception is that some people are only in pain because they are weak, anxious, depressed, or do not deal well with stress.…](https://sms4smile.com/quotes/tasha-stanton/a-common-misconception-is-that-some-people-are-only-in-pain-because/) Tasha Stanton > [“Everyone experiences pain and most suffer from patterns that continue to make life miserable unless something or someone intervenes. The pain we feel comes…](https://sms4smile.com/quotes/michael-meade/everyone-experiences-pain-and-most-suffer-from-patterns-that-continue/) [Michael Meade](https://sms4smile.com/quotes/author/michael-meade/) > [“If you've gone through pain now, learned your lesson, chances are, you'll probably experience MINOR pain later in life. If you haven't witnessed any…](https://sms4smile.com/quotes/amrita-ramanathan/if-you-ve-gone-through-pain-now-learned-your-lesson-chances-are-you/) Amrita Ramanathan > [I've always protected myself when it comes to love. And maybe that's the problem. By not letting myself get hurt now, it ripples into…](https://sms4smile.com/quotes/carolyn-mackler/i-ve-always-protected-myself-when-it-comes-to-love-and-maybe-that-s/) [Carolyn Mackler](https://sms4smile.com/quotes/author/carolyn-mackler/) > [“Sometimes we bookmark our pain so later we may come back to it.”](https://sms4smile.com/quotes/dean-freeberg/sometimes-we-bookmark-our-pain-so-later-we-may-come-back-to-it/) Dean Freeberg > [Human beings are members of a whole, In creation of one essence and soul. If one member is afflicted with pain, Other members uneasy…](https://sms4smile.com/quotes/saadi/human-beings-are-members-of-a-whole-in-creation-of-one-essence-and/) [Saadi](https://sms4smile.com/quotes/author/saadi/) > [If you think for one second no one knows what you've been going through; be accepting of the fact that you are wrong, that…](https://sms4smile.com/quotes/shane-koyczan/if-you-think-for-one-second-no-one-knows-what-you-ve-been-going/) [Shane Koyczan](https://sms4smile.com/quotes/author/shane-koyczan/) > [There certainly are people who are a pain to work with. I'd be crazy to name them. You can't be indiscreet in this business.](https://sms4smile.com/quotes/annie-leibovitz/there-certainly-are-people-who-are-a-pain-to-work-with-i-d-be-crazy/) [Annie Leibovitz](https://sms4smile.com/quotes/author/annie-leibovitz/) > [pain can work form the outside in.](https://sms4smile.com/quotes/jack-ketchum/pain-can-work-form-the-outside-in/) [Jack Ketchum](https://sms4smile.com/quotes/author/jack-ketchum/) > [“Let pain work for you, not against you.”](https://sms4smile.com/quotes/matshona-dhliwayo/let-pain-work-for-you-not-against-you/) [Matshona Dhliwayo](https://sms4smile.com/quotes/author/matshona-dhliwayo/) > [Work done for the Self gives no bondage. Neither desire pleasure nor fear pain from work. It is the mind and body that work,…](https://sms4smile.com/quotes/swami-vivekananda/work-done-for-the-self-gives-no-bondage-neither-desire-pleasure-nor/) [Swami Vivekananda](https://sms4smile.com/quotes/author/swami-vivekananda/) > [The toughest workout can never match the pain of being out of work.](https://sms4smile.com/quotes/george-montgomery/the-toughest-workout-can-never-match-the-pain-of-being-out-of-work/) George Montgomery > [In Heaven we shall not rest from our work, but from our labors. There will be no toil, no pain in the work.](https://sms4smile.com/quotes/david-berg/in-heaven-we-shall-not-rest-from-our-work-but-from-our-labors-there/) [David Berg](https://sms4smile.com/quotes/author/david-berg/) > [“Sometimes it is nothing more than gritting your teeth through pain, and the work of every day, the slow walk toward a better life.”](https://sms4smile.com/quotes/veronica-roth/sometimes-it-is-nothing-more-than-gritting-your-teeth-through-pain/) [Veronica Roth](https://sms4smile.com/quotes/author/veronica-roth/) > [The Gnostics believed that exile was the essential condition of man. Do you agree? I do. The artist and the addict both wrestle with…](https://sms4smile.com/quotes/steven-pressfield/the-gnostics-believed-that-exile-was-the-essential-condition-of-man/) [Steven Pressfield](https://sms4smile.com/quotes/author/steven-pressfield/) ## More by Lisa Feldman Barrett > [“Your body-budgeting regions can therefore trick your brain into believing that there is tissue damage, regardless of what is happening in your body. So,…](https://sms4smile.com/quotes/lisa-feldman-barrett/your-body-budgeting-regions-can-therefore-trick-your-brain-into/) [Lisa Feldman Barrett](https://sms4smile.com/quotes/author/lisa-feldman-barrett/) > [“The word “smile” doesn’t even exist in Latin or Ancient Greek. Smiling was an invention of the Middle Ages, and broad, toothy-mouthed smiles (with…](https://sms4smile.com/quotes/lisa-feldman-barrett/the-word-smile-doesn-t-even-exist-in-latin-or-ancient-greek-smiling/) [Lisa Feldman Barrett](https://sms4smile.com/quotes/author/lisa-feldman-barrett/) > [“Our words allow us to enter each other’s affective niches, even at extremely long distances. You can regulate your friend’s body budget (and he…](https://sms4smile.com/quotes/lisa-feldman-barrett/our-words-allow-us-to-enter-each-other-s-affective-niches-even-at/) [Lisa Feldman Barrett](https://sms4smile.com/quotes/author/lisa-feldman-barrett/) > [“The human brain is a cultural artifact. We don't load culture into a virgin brain like software loading into a computer; rather, culture helps…](https://sms4smile.com/quotes/lisa-feldman-barrett/the-human-brain-is-a-cultural-artifact-we-don-t-load-culture-into-a/) [Lisa Feldman Barrett](https://sms4smile.com/quotes/author/lisa-feldman-barrett/) > [“Your brain is shaped by the realities of the world that you find yourself in, including the social world made by agreement among people.…](https://sms4smile.com/quotes/lisa-feldman-barrett/your-brain-is-shaped-by-the-realities-of-the-world-that-you-find/) [Lisa Feldman Barrett](https://sms4smile.com/quotes/author/lisa-feldman-barrett/) > [“In other words, the Himba participants categorized facial movements as behaviors rather than inferring mental states or feelings.”](https://sms4smile.com/quotes/lisa-feldman-barrett/in-other-words-the-himba-participants-categorized-facial-movements-as/) [Lisa Feldman Barrett](https://sms4smile.com/quotes/author/lisa-feldman-barrett/) > [“This is another basis for my frequent claim, “You are an architect of your experience.” You are indeed partly responsible for your actions, even…](https://sms4smile.com/quotes/lisa-feldman-barrett/this-is-another-basis-for-my-frequent-claim-you-are-an-architect-of/) [Lisa Feldman Barrett](https://sms4smile.com/quotes/author/lisa-feldman-barrett/) > [“A similar bout of affective realism gave birth to Florida’s controversial “Stand Your Ground” law. This law permits the use of deadly force in…](https://sms4smile.com/quotes/lisa-feldman-barrett/a-similar-bout-of-affective-realism-gave-birth-to-florida-s/) [Lisa Feldman Barrett](https://sms4smile.com/quotes/author/lisa-feldman-barrett/) > [“Western culture has some common wisdom associated with these ideas. Don’t be materialistic. What doesn’t kill us makes us stronger. Sticks and stones. But…](https://sms4smile.com/quotes/lisa-feldman-barrett/western-culture-has-some-common-wisdom-associated-with-these-ideas/) [Lisa Feldman Barrett](https://sms4smile.com/quotes/author/lisa-feldman-barrett/) > [“But one thing is certain: every day in America, thousands of people appear before a jury of their peers and hope they will be…](https://sms4smile.com/quotes/lisa-feldman-barrett/but-one-thing-is-certain-every-day-in-america-thousands-of-people/) [Lisa Feldman Barrett](https://sms4smile.com/quotes/author/lisa-feldman-barrett/) > [“Anger is stereotypically normal for men because they are supposed to be aggressors. Women are supposed to be victims, and good victims shouldn’t become…](https://sms4smile.com/quotes/lisa-feldman-barrett/anger-is-stereotypically-normal-for-men-because-they-are-supposed-to/) [Lisa Feldman Barrett](https://sms4smile.com/quotes/author/lisa-feldman-barrett/) > [“It is actually a policy issue relevant to the First Amendment, which guarantees the right to free speech. The First Amendment was founded on…](https://sms4smile.com/quotes/lisa-feldman-barrett/it-is-actually-a-policy-issue-relevant-to-the-first-amendment-which/) [Lisa Feldman Barrett](https://sms4smile.com/quotes/author/lisa-feldman-barrett/) > [“Scientific revolutions tend to emerge not from a sudden discovery but by asking better questions”](https://sms4smile.com/quotes/lisa-feldman-barrett/scientific-revolutions-tend-to-emerge-not-from-a-sudden-discovery-but/) [Lisa Feldman Barrett](https://sms4smile.com/quotes/author/lisa-feldman-barrett/) > [“I can notice a tiny weed forcing its way through a crack in the sidewalk, proving yet again that nature cannot be tamed by…](https://sms4smile.com/quotes/lisa-feldman-barrett/i-can-notice-a-tiny-weed-forcing-its-way-through-a-crack-in-the/) [Lisa Feldman Barrett](https://sms4smile.com/quotes/author/lisa-feldman-barrett/) > [“I’ve said several times that the brain acts like a scientist. It forms hypotheses through prediction and tests them against the “data” of sensory…](https://sms4smile.com/quotes/lisa-feldman-barrett/i-ve-said-several-times-that-the-brain-acts-like-a-scientist-it-forms/) [Lisa Feldman Barrett](https://sms4smile.com/quotes/author/lisa-feldman-barrett/) [Explore all 35 Lisa Feldman Barrett quotes ](https://sms4smile.com/quotes/author/lisa-feldman-barrett/) ## More Chronic pain quotes > [“Every EDS patient knows that one of the hardest parts of our day is the moment we open our eyes and waken into the…](https://sms4smile.com/quotes/michael-bihovsky/every-eds-patient-knows-that-one-of-the-hardest-parts-of-our-day-is/) [Michael Bihovsky](https://sms4smile.com/quotes/author/michael-bihovsky/) > [“There’s such a thing as chronic pain, but there’s no such thing as chronic pleasure. ... For an existing person, the presence of bad…](https://sms4smile.com/quotes/david-benatar/there-s-such-a-thing-as-chronic-pain-but-there-s-no-such-thing-as/) [David Benatar](https://sms4smile.com/quotes/author/david-benatar/) > [“Mental illness People assume you aren’t sick unless they see the sickness on your skin like scars forming a map of all the ways…](https://sms4smile.com/quotes/emm-roy/mental-illness-people-assume-you-aren-t-sick-unless-they-see-the/) Emm Roy > [“Sometimes, this disapproval of how you are managing your pain crosses over to disbelief that you are in as much pain as you say…](https://sms4smile.com/quotes/murray-j-mcalister/sometimes-this-disapproval-of-how-you-are-managing-your-pain-crosses/) Murray J. McAlister > [The lesion is in the area of my brain that is responsible for motor function, so I have continual chronic pain in my left…](https://sms4smile.com/quotes/karen-duffy/the-lesion-is-in-the-area-of-my-brain-that-is-responsible-for-motor/) [Karen Duffy](https://sms4smile.com/quotes/author/karen-duffy/) > [“In the debate over opioid addiction, there’s one group we aren’t hearing from: chronic pain patients, many of whom need to use the drugs…](https://sms4smile.com/quotes/s-e-smith-2/in-the-debate-over-opioid-addiction-there-s-one-group-we-aren-t/) S. E. Smith > [I literally couldn't walk down the street; I slept for 16 hours a day, was in chronic pain, had blackouts, never-ending heart palpitations, unbearable…](https://sms4smile.com/quotes/ella-woodward/i-literally-couldn-t-walk-down-the-street-i-slept-for-16-hours-a-day/) [Ella Woodward](https://sms4smile.com/quotes/author/ella-woodward/) > [“Government agencies are trying to get doctors to cut back on prescribing opioids. I understand that they need to do something about the epidemic…](https://sms4smile.com/quotes/alison-moore/government-agencies-are-trying-to-get-doctors-to-cut-back-on/) [Alison Moore](https://sms4smile.com/quotes/author/alison-moore/) > [I've always loved animals. I've never lived without them. As long as I can remember, I was bringing home strays. When I was five,…](https://sms4smile.com/quotes/ken-wahl/i-ve-always-loved-animals-i-ve-never-lived-without-them-as-long-as-i/) [Ken Wahl](https://sms4smile.com/quotes/author/ken-wahl/) > [I shake all the time. It's exhausting and causes chronic pain in my joints and muscles. It is also the only life I have…](https://sms4smile.com/quotes/maysoon-zayid/i-shake-all-the-time-it-s-exhausting-and-causes-chronic-pain-in-my/) [Maysoon Zayid](https://sms4smile.com/quotes/author/maysoon-zayid/) > [I think anyone who suffers from chronic pain can agree with this - you feel this great significance. What I wanted to capture was…](https://sms4smile.com/quotes/phil-anselmo/i-think-anyone-who-suffers-from-chronic-pain-can-agree-with-this-you/) [Phil Anselmo](https://sms4smile.com/quotes/author/phil-anselmo/) > [“Not every day is awful. Not every day is good. Despite the way the hours pass, I’m living like I should. Not every day…](https://sms4smile.com/quotes/richelle-e-goodrich/not-every-day-is-awful-not-every-day-is-good-despite-the-way-the/) [Richelle E. Goodrich](https://sms4smile.com/quotes/author/richelle-e-goodrich/) > [“I had learned quickly that life doesn't always go the way I want it to, and that's okay. I still plod on.”](https://sms4smile.com/quotes/sarah-todd-hammer/i-had-learned-quickly-that-life-doesn-t-always-go-the-way-i-want-it/) [Sarah Todd Hammer](https://sms4smile.com/quotes/author/sarah-todd-hammer/) > [The only way to truly understand someones chronic pain...is to experience that pain yourself, which you probably never will.](https://sms4smile.com/quotes/azgraybebly-joslan/the-only-way-to-truly-understand-someones-chronic-pain-is-to/) Azgraybebly Joslan > [“Pushing ourselves to do too much despite the pain will not result in gain but may cause additional injury. However, sometimes we do need…](https://sms4smile.com/quotes/karen-lee-richards/pushing-ourselves-to-do-too-much-despite-the-pain-will-not-result-in/) Karen Lee Richards [Browse all 120 Chronic pain quotes ](https://sms4smile.com/quotes/about/chronic-pain/) ```json { "@context": "https://schema.org", "@graph": [ { "@type": "Quotation", "text": "“We already have intriguing evidence that some types of chronic pain work by prediction. Animals who have stress or injury early in life become more likely to develop persistent pain. Human infants who have surgery are more likely to have heightened pain in later childhood. 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