--- title: "Meaning & Key Takeaway of: Severe, persisting fatigue is a prominent…" description: "\"“Severe, persisting fatigue is a prominent symptom of Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS), but individuals with this illness fr..." image: "https://sms4smile.com/quotes/i/7bc/leonard-a-jason-49563_cfs_severe-persisting-fatigue-is-a-prominent_1478576.jpg" --- # Severe, persisting fatigue is a prominent symptom of… ![“Severe, persisting fatigue is a prominent symptom of Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS), but individuals with this illness frequently report the occurrence of unique fatigue states that might be different from conventional symptoms of fatigue.” quote by Leonard A. Jason](https://sms4smile.com/quotes/i/7bc/leonard-a-jason-49563_cfs_severe-persisting-fatigue-is-a-prominent_1478576.jpg) [Download](https://sms4smile.com/quotes/i/7bc/leonard-a-jason-49563_cfs_severe-persisting-fatigue-is-a-prominent_1478576.jpg) [Open image](https://sms4smile.com/quotes/i/7bc/leonard-a-jason-49563_cfs_severe-persisting-fatigue-is-a-prominent_1478576.jpg) > ““Severe, persisting fatigue is a prominent symptom of Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS), but individuals with this illness frequently report the occurrence of unique fatigue states that might be different from conventional symptoms of fatigue.”” [Leonard A. Jason](https://sms4smile.com/quotes/author/leonard-a-jason/) ## About This Quote This interpretation was drafted with AI assistance. It is one reading of the quote, not the author's own explanation. Patients with ME/CFS often experience fatigue that differs from typical tiredness, indicating a unique symptom profile. **In simple terms:** ME/CFS fatigue can be distinct from ordinary fatigue. Key Takeaway Recognize and address diverse fatigue experiences. Themes health medicine patient experience Mood empathetic informative Type medical scientific When to use this quote - clinical assessment - patient counseling - research design Key Concepts symptom variability chronic illness clinical research Questions to Reflect On - What clinical approaches can address these unique fatigue states? - How can clinicians differentiate these symptoms from other conditions? A Different Perspective The description may lack practical guidance for treatment strategies. ★ ★ ★ ★ ★ No ratings yet [Cfs](https://sms4smile.com/quotes/about/cfs/) [Chronic fatigue](https://sms4smile.com/quotes/about/chronic-fatigue/) [Chronic-fatigue-syndrome](https://sms4smile.com/quotes/about/chronic-fatigue-syndrome/) [Fatigue](https://sms4smile.com/quotes/about/fatigue/) [Fatigue States](https://sms4smile.com/quotes/about/fatigue-states-5383312/) [Fatigue Syndrome](https://sms4smile.com/quotes/about/fatigue-syndrome-907971/) [M-e](https://sms4smile.com/quotes/about/m-e/) [M-e-cfs](https://sms4smile.com/quotes/about/m-e-cfs/) [Me-cfs](https://sms4smile.com/quotes/about/me-cfs/) [Myalgic-encephalomyelitis](https://sms4smile.com/quotes/about/myalgic-encephalomyelitis/) [Persisting Fatigue](https://sms4smile.com/quotes/about/persisting-fatigue-5383311/) [Unique Fatigue](https://sms4smile.com/quotes/about/unique-fatigue-5383313/) ## Related quotes > [“Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling condition characterized by severe unexplained fatigue and a mixed profile of symptoms such as sore throat,…](https://sms4smile.com/quotes/leonard-a-jason/myalgic-encephalomyelitis-chronic-fatigue-syndrome-me-cfs-is-a/) [Leonard A. Jason](https://sms4smile.com/quotes/author/leonard-a-jason/) > [“Although myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS) are considered to be synonymous, the definitional criteria for ME and CFS define two distinct,…](https://sms4smile.com/quotes/frank-twisk/although-myalgic-encephalomyelitis-me-and-chronic-fatigue-syndrome/) [Frank Twisk](https://sms4smile.com/quotes/author/frank-twisk/) > [“The diagnostic criteria for myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS) define two distinct clinical entities. Cognitive impairment and post-exertional “malaise” (a long-lasting…](https://sms4smile.com/quotes/frank-twisk/the-diagnostic-criteria-for-myalgic-encephalomyelitis-me-and-chronic/) [Frank Twisk](https://sms4smile.com/quotes/author/frank-twisk/) > [“The label ‘Chronic Fatigue Syndrome’ was first proposed by Holmes et al. (1988) of the Centers for Disease Control (CDC). This name was recommended…](https://sms4smile.com/quotes/megan-a-arroll/the-label-chronic-fatigue-syndrome-was-first-proposed-by-holmes-et-al/) [Megan A. Arroll](https://sms4smile.com/quotes/author/megan-a-arroll/) > [ “The finding that ME and CFS group had more functional limitations and more serious symptoms than those with MS \[multiple sclerosis\] provides additional evidence… ](https://sms4smile.com/quotes/leonard-a-jason/the-finding-that-me-and-cfs-group-had-more-functional-limitations-and/) [Leonard A. Jason](https://sms4smile.com/quotes/author/leonard-a-jason/) > [“individuals with ME/CFS experience different types of fatigue than what are reported in the general populations”](https://sms4smile.com/quotes/leonard-a-jason/individuals-with-me-cfs-experience-different-types-of-fatigue-than/) [Leonard A. Jason](https://sms4smile.com/quotes/author/leonard-a-jason/) > [“the disabling fatigue experienced by individuals with ME/CFS differs from that associated with other illnesses or everyday activity”](https://sms4smile.com/quotes/leonard-a-jason/the-disabling-fatigue-experienced-by-individuals-with-me-cfs-differs/) [Leonard A. Jason](https://sms4smile.com/quotes/author/leonard-a-jason/) > [“Finally, individuals with severe pathological fatigue might experience states that are very different from what a healthy individual experiences when fatigued.”](https://sms4smile.com/quotes/leonard-a-jason/finally-individuals-with-severe-pathological-fatigue-might-experience/) [Leonard A. Jason](https://sms4smile.com/quotes/author/leonard-a-jason/) > [“Many people confuse “chronic fatigue” (which is a symptom of many chronic conditions, including rheumatoid arthritis, fibromyalgia, or lupus) or “general tiredness” (which is…](https://sms4smile.com/quotes/valerie-free/many-people-confuse-chronic-fatigue-which-is-a-symptom-of-many/) [Valerie free](https://sms4smile.com/quotes/author/valerie-free/) > [“To differentiate between symptoms of depression and anxiety secondary to ME/CFS and psychiatric disorders, ask the patient what they will do the next time…](https://sms4smile.com/quotes/alison-c-bested/to-differentiate-between-symptoms-of-depression-and-anxiety-secondary/) [Alison C. Bested](https://sms4smile.com/quotes/author/alison-c-bested/) > [“Malaise” is a general body discomfort or weakness, often marking the onset of an of infection/flu-like illness or other disease. Fatigue and flu-like symptoms…](https://sms4smile.com/quotes/alison-c-bested/malaise-is-a-general-body-discomfort-or-weakness-often-marking-the/) [Alison C. Bested](https://sms4smile.com/quotes/author/alison-c-bested/) > [ “ME/CFS has a greater negative impact on functional status and well-being than other chronic diseases, e.g., cancer or lung diseases\[8\], and is associated with… ](https://sms4smile.com/quotes/frank-twisk/me-cfs-has-a-greater-negative-impact-on-functional-status-and-well/) [Frank Twisk](https://sms4smile.com/quotes/author/frank-twisk/) > [“Over the years, I have cared for loved ones with advanced Alzheimer, late stage cardiovascular and renal disease and Stage 4 cancer. But none…](https://sms4smile.com/quotes/mary-dimmock/over-the-years-i-have-cared-for-loved-ones-with-advanced-alzheimer/) [Mary Dimmock](https://sms4smile.com/quotes/author/mary-dimmock/) > [“All I ask of all my friends is that they understand this is truly a devastating neurological illness and not just about being a…](https://sms4smile.com/quotes/tracey-browett/all-i-ask-of-all-my-friends-is-that-they-understand-this-is-truly-a/) [Tracey Browett](https://sms4smile.com/quotes/author/tracey-browett/) > [“The single biggest factor determining recovery and remission from Myalgic Encephalomyelitis (M.E.) at this point is undoubtedly appropriate rest in the early and/or severe…](https://sms4smile.com/quotes/jodi-bassett/the-single-biggest-factor-determining-recovery-and-remission-from/) [Jodi Bassett](https://sms4smile.com/quotes/author/jodi-bassett/) ## More by Leonard A. Jason > [“Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling condition characterized by severe unexplained fatigue and a mixed profile of symptoms such as sore throat,…](https://sms4smile.com/quotes/leonard-a-jason/myalgic-encephalomyelitis-chronic-fatigue-syndrome-me-cfs-is-a/) [Leonard A. Jason](https://sms4smile.com/quotes/author/leonard-a-jason/) > [“When people with ME/CFS report symptoms of post-exertional malaise, those symptoms are independent of emotional distress, but when the general population report what they…](https://sms4smile.com/quotes/leonard-a-jason/when-people-with-me-cfs-report-symptoms-of-post-exertional-malaise/) [Leonard A. Jason](https://sms4smile.com/quotes/author/leonard-a-jason/) > [“Finally, individuals with severe pathological fatigue might experience states that are very different from what a healthy individual experiences when fatigued.”](https://sms4smile.com/quotes/leonard-a-jason/finally-individuals-with-severe-pathological-fatigue-might-experience/) [Leonard A. Jason](https://sms4smile.com/quotes/author/leonard-a-jason/) > [“the disabling fatigue experienced by individuals with ME/CFS differs from that associated with other illnesses or everyday activity”](https://sms4smile.com/quotes/leonard-a-jason/the-disabling-fatigue-experienced-by-individuals-with-me-cfs-differs/) [Leonard A. Jason](https://sms4smile.com/quotes/author/leonard-a-jason/) > [“individuals with ME/CFS experience different types of fatigue than what are reported in the general populations”](https://sms4smile.com/quotes/leonard-a-jason/individuals-with-me-cfs-experience-different-types-of-fatigue-than/) [Leonard A. Jason](https://sms4smile.com/quotes/author/leonard-a-jason/) > [ “The finding that ME and CFS group had more functional limitations and more serious symptoms than those with MS \[multiple sclerosis\] provides additional evidence… ](https://sms4smile.com/quotes/leonard-a-jason/the-finding-that-me-and-cfs-group-had-more-functional-limitations-and/) [Leonard A. Jason](https://sms4smile.com/quotes/author/leonard-a-jason/) [Explore all 7 Leonard A. Jason quotes ](https://sms4smile.com/quotes/author/leonard-a-jason/) ## More Cfs quotes > [The Lord came to send fire upon the earth (cf. Lk. 12:49), and through participation in this fire He makes divine not just the…](https://sms4smile.com/quotes/gregory-palamas/the-lord-came-to-send-fire-upon-the-earth-cf-lk-12-49-and-through/) [Gregory Palamas](https://sms4smile.com/quotes/author/gregory-palamas/) > [Gluttony should be destroyed by self-control; unchastity by desire for God and longing for the blessings held in store; avarice by compassion for the…](https://sms4smile.com/quotes/john-of-damascus/gluttony-should-be-destroyed-by-self-control-unchastity-by-desire-for/) [John of Damascus](https://sms4smile.com/quotes/author/john-of-damascus/) > ["If any man thirst, let him come and drink from the rivers of living water" (cf. John 7:38). Where shall he who thirsts come?…](https://sms4smile.com/quotes/cyprian/if-any-man-thirst-let-him-come-and-drink-from-the-rivers-of-living/) [Cyprian](https://sms4smile.com/quotes/author/cyprian/) > [His Majesty knows best what is suitable for us. 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This is inconsistent with the assumption that there is pathological avoidance of…](https://sms4smile.com/quotes/sten-helmfrid/there-are-many-reports-that-suggest-a-biomedical-basis-for-post/) [Sten Helmfrid](https://sms4smile.com/quotes/author/sten-helmfrid/) > [“In July and August 2011 Simon Wessely ran a media campaign with the BBC and the broadsheets, successfully vilifying patients who had justifiably criticised…](https://sms4smile.com/quotes/horace-reid/in-july-and-august-2011-simon-wessely-ran-a-media-campaign-with-the/) [Horace Reid](https://sms4smile.com/quotes/author/horace-reid/) > [Keep the Feast of the Resurrection. 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This name captures a central characteristic of… ](https://sms4smile.com/quotes/ellen-wright-clayton/to-replace-me-cfs-the-institute-of-medicine-committee-proposes-the/) [Ellen Wright Clayton](https://sms4smile.com/quotes/author/ellen-wright-clayton/) > ['The long-suffering man abounds in understanding' (Prov. 14:29), because he endures everything to the end and, while awaiting that end, patiently bears his distress.…](https://sms4smile.com/quotes/maximus-the-confessor/the-long-suffering-man-abounds-in-understanding-prov-14-29-because-he/) [Maximus the Confessor](https://sms4smile.com/quotes/author/maximus-the-confessor/) > [“Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling condition characterized by severe unexplained fatigue and a mixed profile of symptoms such as sore throat,…](https://sms4smile.com/quotes/leonard-a-jason/myalgic-encephalomyelitis-chronic-fatigue-syndrome-me-cfs-is-a/) [Leonard A. Jason](https://sms4smile.com/quotes/author/leonard-a-jason/) [Browse all 134 Cfs quotes ](https://sms4smile.com/quotes/about/cfs/) ```json { "@context": "https://schema.org", "@graph": [ { "@type": "Quotation", "text": "“Severe, persisting fatigue is a prominent symptom of Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS), but individuals with this illness frequently report the occurrence of unique fatigue states that might be different from conventional symptoms of fatigue.”", "creator": { "@type": "Person", "name": "Leonard A. 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