--- title: "Meaning & Key Takeaway of: when the omega-3 fats EPA and DHA are…" description: "\"“when the omega-3 fats EPA and DHA are oxidized, they significantly activate the Nrf2 pathway. For”\" — David Perlmutter" image: "https://sms4smile.com/quotes/i/fab/david-perlmutter-2461_food_when-the-omega-3-fats-epa-and-dha-are-ox_1564473.png" --- # when the omega-3 fats EPA and DHA are oxidized, they… ![“when the omega-3 fats EPA and DHA are oxidized, they significantly activate the Nrf2 pathway. For” quote by David Perlmutter](https://sms4smile.com/quotes/i/fab/david-perlmutter-2461_food_when-the-omega-3-fats-epa-and-dha-are-ox_1564473.png) [Download](https://sms4smile.com/quotes/i/fab/david-perlmutter-2461_food_when-the-omega-3-fats-epa-and-dha-are-ox_1564473.png) [Open image](https://sms4smile.com/quotes/i/fab/david-perlmutter-2461_food_when-the-omega-3-fats-epa-and-dha-are-ox_1564473.png) > ““when the omega-3 fats EPA and DHA are oxidized, they significantly activate the Nrf2 pathway. For”” [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) ## About This Quote This interpretation was drafted with AI assistance. It is one reading of the quote, not the author's own explanation. Oxidized omega‑3s (EPA/DHA) activate the Nrf2 pathway, supporting cellular defense and longevity **In simple terms:** EPA/DHA oxidation boosts Nrf2, aiding health defense Key Takeaway Include omega‑3 rich foods to support antioxidant pathways Themes nutrition longevity cellular health Mood informative optimistic Type scientific health When to use this quote - diet planning - supplement choice - aging research Key Concepts Biochemistry nutrigenomics Questions to Reflect On - How can you ensure omega‑3s remain beneficial rather than harmful? - What lifestyle factors enhance Nrf2 activation? A Different Perspective Excess oxidation can produce harmful byproducts if not balanced ★ ★ ★ ★ ★ No ratings yet [Food](https://sms4smile.com/quotes/about/food/) ## Related quotes > [“coffee is one of the most powerful Nrf2 activators in nature. Several molecules in coffee, some of which are partly present in the raw…](https://sms4smile.com/quotes/david-perlmutter/coffee-is-one-of-the-most-powerful-nrf2-activators-in-nature-several/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“omega-6 fats, which are found in many vegetable oils, including safflower oil, corn oil, canola oil, sunflower oil, and soybean oil; vegetable oil represents…](https://sms4smile.com/quotes/david-perlmutter/omega-6-fats-which-are-found-in-many-vegetable-oils-including/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“hunter-gatherer ancestors consumed omega-6 and omega-3 fats in a ratio of roughly 1:1.”](https://sms4smile.com/quotes/david-perlmutter/hunter-gatherer-ancestors-consumed-omega-6-and-omega-3-fats-in-a/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“omega-6 fats fall under the “bad fat” category; they are somewhat pro-inflammatory, and there is evidence that higher consumption of these fats is related…](https://sms4smile.com/quotes/david-perlmutter/omega-6-fats-fall-under-the-bad-fat-category-they-are-somewhat-pro/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“Cold-water, fatty fishes such as salmon, sardines, cod, haddock, and mackerel are highest in omega-3 fats. You may also enjoy shellfish such as mussels,…](https://sms4smile.com/quotes/john-chatham/cold-water-fatty-fishes-such-as-salmon-sardines-cod-haddock-and/) [John Chatham](https://sms4smile.com/quotes/author/john-chatham/) > [“Nine times out of ten, people pick the wrong food. No, it’s not the sugar (GI = 68), it’s not the candy bar (GI…](https://sms4smile.com/quotes/david-perlmutter/nine-times-out-of-ten-people-pick-the-wrong-food-no-it-s-not-the/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“if you cannot control your hunger and appetite, good luck managing your blood chemistry, metabolism, waistline, and, in the bigger picture, the prospect of…](https://sms4smile.com/quotes/david-perlmutter/if-you-cannot-control-your-hunger-and-appetite-good-luck-managing/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [ “\[S\]ometimes, when you are a food person, the possible irrelevance of what you are doing doesn’t cross your mind until it’s too late. (Once,… ](https://sms4smile.com/quotes/nora-ephron/s-ometimes-when-you-are-a-food-person-the-possible-irrelevance-of/) [Nora Ephron](https://sms4smile.com/quotes/author/nora-ephron/) > [To me, Caribbean food is about fresh, seasonal produce - using what's in season to create vibrant and great tasting food. The spicing is…](https://sms4smile.com/quotes/ainsley-harriott/to-me-caribbean-food-is-about-fresh-seasonal-produce-using-what-s-in/) [Ainsley Harriott](https://sms4smile.com/quotes/author/ainsley-harriott/) > [I feel like I could eat the world raw.](https://sms4smile.com/quotes/madeline-miller/i-feel-like-i-could-eat-the-world-raw/) [Madeline Miller](https://sms4smile.com/quotes/author/madeline-miller/) > [“My God, Joseph, your toasted sandwiches are the fucking shit. You do know that right?”](https://sms4smile.com/quotes/beth-ashworth/my-god-joseph-your-toasted-sandwiches-are-the-fucking-shit-you-do/) [Beth Ashworth](https://sms4smile.com/quotes/author/beth-ashworth/) > [“The global population of Earth are involved in the following corporate government experiments: The long term effects of - 1. Nuclear bomb fallout radiation.…](https://sms4smile.com/quotes/steven-magee/the-global-population-of-earth-are-involved-in-the-following/) [Steven Magee](https://sms4smile.com/quotes/author/steven-magee/) > [By eating many fruits and vegetables in place of fast food and junk food, people could avoid obesity.](https://sms4smile.com/quotes/david-h-murdock/by-eating-many-fruits-and-vegetables-in-place-of-fast-food-and-junk/) [David H. Murdock](https://sms4smile.com/quotes/author/david-h-murdock/) > [Before Noah, men having only water to drink, could not find the truth. Accordingly...they became abominably wicked, and they were justly exterminated by the…](https://sms4smile.com/quotes/benjamin-franklin/before-noah-men-having-only-water-to-drink-could-not-find-the-truth/) [Benjamin Franklin](https://sms4smile.com/quotes/author/benjamin-franklin/) > [On Sundays, that's my pig out day and I do the pizza and the beer.](https://sms4smile.com/quotes/victoria-silvstedt/on-sundays-that-s-my-pig-out-day-and-i-do-the-pizza-and-the-beer/) [Victoria Silvstedt](https://sms4smile.com/quotes/author/victoria-silvstedt/) ## More by David Perlmutter > [“if you cannot control your hunger and appetite, good luck managing your blood chemistry, metabolism, waistline, and, in the bigger picture, the prospect of…](https://sms4smile.com/quotes/david-perlmutter/if-you-cannot-control-your-hunger-and-appetite-good-luck-managing/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“Nine times out of ten, people pick the wrong food. No, it’s not the sugar (GI = 68), it’s not the candy bar (GI…](https://sms4smile.com/quotes/david-perlmutter/nine-times-out-of-ten-people-pick-the-wrong-food-no-it-s-not-the/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“Your brain… weighs three pounds and has one hundred thousand miles of blood vessels. contains more connections than there are stars in the Milky…](https://sms4smile.com/quotes/david-perlmutter/your-brain-weighs-three-pounds-and-has-one-hundred-thousand-miles-of/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [Inflammation is the cornerstone of Alzheimer's disease and Parkinson's, multiple sclerosis - all of the neurodegenerative diseases are really predicated on inflammation.](https://sms4smile.com/quotes/david-perlmutter/inflammation-is-the-cornerstone-of-alzheimer-s-disease-and-parkinson/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“Those who experience symptoms complain of abdominal pain, nausea, diarrhea, constipation, and intestinal distress. Some people, however, don’t experience obvious signs of gastrointestinal trouble,…](https://sms4smile.com/quotes/david-perlmutter/those-who-experience-symptoms-complain-of-abdominal-pain-nausea/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [Saturated fat is a fundamental building block for brain cells. It's certainly interesting to consider that one of the richest sources of saturated fat…](https://sms4smile.com/quotes/david-perlmutter/saturated-fat-is-a-fundamental-building-block-for-brain-cells-it-s/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“THE GLUTEN POLICE The following grains and starches contain gluten: barley bulgur couscous farina graham flour kamut matzo rye semolina spelt triticale wheat wheat…](https://sms4smile.com/quotes/david-perlmutter/the-gluten-police-the-following-grains-and-starches-contain-gluten/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“people with celiac have significantly increased production of free radicals, and they exhibit free radical damage to their fat, protein, and even DNA.16 In…](https://sms4smile.com/quotes/david-perlmutter/people-with-celiac-have-significantly-increased-production-of-free/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“The bile salts secreted by the gallbladder, which are needed for the digestion of fat and, therefore, the absorption of fat-soluble vitamins like A,…](https://sms4smile.com/quotes/david-perlmutter/the-bile-salts-secreted-by-the-gallbladder-which-are-needed-for-the/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“According to the latest research, we owe our tremendous brains to the need to think… and the need to run.”](https://sms4smile.com/quotes/david-perlmutter/according-to-the-latest-research-we-owe-our-tremendous-brains-to-the/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [Most grain foods, whether we're talking about quinoa, amaranth, the very popular grains of the day - the reality is they still are associated…](https://sms4smile.com/quotes/david-perlmutter/most-grain-foods-whether-we-re-talking-about-quinoa-amaranth-the-very/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“reduce the risk of LDL oxidation—not necessarily levels of LDL itself. A principal player in that risk of oxidation is higher levels of glucose;…](https://sms4smile.com/quotes/david-perlmutter/reduce-the-risk-of-ldl-oxidation-not-necessarily-levels-of-ldl-itself/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [People are getting to this place of understanding that their lifestyle choices actually do matter a whole lot as opposed to this notion that…](https://sms4smile.com/quotes/david-perlmutter/people-are-getting-to-this-place-of-understanding-that-their/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“What you eat & when you eat matter, but so does what order you eat your foods in. Never eat what Dr. Casey Means…](https://sms4smile.com/quotes/david-perlmutter/what-you-eat-when-you-eat-matter-but-so-does-what-order-you-eat-your/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“The results of the study revealed that those individuals in the lowest 10 percent of daily physical activity had a 230 percent increased risk…](https://sms4smile.com/quotes/david-perlmutter/the-results-of-the-study-revealed-that-those-individuals-in-the/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) [Explore all 163 David Perlmutter quotes ](https://sms4smile.com/quotes/author/david-perlmutter/) ## More Food quotes > [On Sundays, that's my pig out day and I do the pizza and the beer.](https://sms4smile.com/quotes/victoria-silvstedt/on-sundays-that-s-my-pig-out-day-and-i-do-the-pizza-and-the-beer/) [Victoria Silvstedt](https://sms4smile.com/quotes/author/victoria-silvstedt/) > [Before Noah, men having only water to drink, could not find the truth. Accordingly...they became abominably wicked, and they were justly exterminated by the…](https://sms4smile.com/quotes/benjamin-franklin/before-noah-men-having-only-water-to-drink-could-not-find-the-truth/) [Benjamin Franklin](https://sms4smile.com/quotes/author/benjamin-franklin/) > [By eating many fruits and vegetables in place of fast food and junk food, people could avoid obesity.](https://sms4smile.com/quotes/david-h-murdock/by-eating-many-fruits-and-vegetables-in-place-of-fast-food-and-junk/) [David H. Murdock](https://sms4smile.com/quotes/author/david-h-murdock/) > [“The global population of Earth are involved in the following corporate government experiments: The long term effects of - 1. Nuclear bomb fallout radiation.…](https://sms4smile.com/quotes/steven-magee/the-global-population-of-earth-are-involved-in-the-following/) [Steven Magee](https://sms4smile.com/quotes/author/steven-magee/) > [“My God, Joseph, your toasted sandwiches are the fucking shit. You do know that right?”](https://sms4smile.com/quotes/beth-ashworth/my-god-joseph-your-toasted-sandwiches-are-the-fucking-shit-you-do/) [Beth Ashworth](https://sms4smile.com/quotes/author/beth-ashworth/) > [I feel like I could eat the world raw.](https://sms4smile.com/quotes/madeline-miller/i-feel-like-i-could-eat-the-world-raw/) [Madeline Miller](https://sms4smile.com/quotes/author/madeline-miller/) > [To me, Caribbean food is about fresh, seasonal produce - using what's in season to create vibrant and great tasting food. The spicing is…](https://sms4smile.com/quotes/ainsley-harriott/to-me-caribbean-food-is-about-fresh-seasonal-produce-using-what-s-in/) [Ainsley Harriott](https://sms4smile.com/quotes/author/ainsley-harriott/) > [ “\[S\]ometimes, when you are a food person, the possible irrelevance of what you are doing doesn’t cross your mind until it’s too late. (Once,… ](https://sms4smile.com/quotes/nora-ephron/s-ometimes-when-you-are-a-food-person-the-possible-irrelevance-of/) [Nora Ephron](https://sms4smile.com/quotes/author/nora-ephron/) > [“if you cannot control your hunger and appetite, good luck managing your blood chemistry, metabolism, waistline, and, in the bigger picture, the prospect of…](https://sms4smile.com/quotes/david-perlmutter/if-you-cannot-control-your-hunger-and-appetite-good-luck-managing/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“Hungarian Proverb: A dish of cabbages can be heated when it grows cold, but it will never taste the same.”](https://sms4smile.com/quotes/mourid-barghouti/hungarian-proverb-a-dish-of-cabbages-can-be-heated-when-it-grows-cold/) [Mourid Barghouti](https://sms4smile.com/quotes/author/mourid-barghouti/) > [“The phrase “low and slow” was coined to describe the relatively low temperatures used for smoking and the lengthy amount of time it takes…](https://sms4smile.com/quotes/ted-reader/the-phrase-low-and-slow-was-coined-to-describe-the-relatively-low/) Ted Reader > [Things live and die, and then someone processes them into edible portions. This is a complete telling of the story, 'Food.' The basic plot…](https://sms4smile.com/quotes/david-fahrenthold/things-live-and-die-and-then-someone-processes-them-into-edible/) [David Fahrenthold](https://sms4smile.com/quotes/author/david-fahrenthold/) > [“Live is like a box of chocolates, we are all just waiting for a hungry hand to come down and grab us and eat…](https://sms4smile.com/quotes/sunshine/live-is-like-a-box-of-chocolates-we-are-all-just-waiting-for-a-hungry/) [sunshine](https://sms4smile.com/quotes/author/sunshine/) > [Sometimes, when full and in fear that I will continue to eat unwanted food just because it's staring at me, I will place my…](https://sms4smile.com/quotes/rachel-nichols/sometimes-when-full-and-in-fear-that-i-will-continue-to-eat-unwanted/) [Rachel Nichols](https://sms4smile.com/quotes/author/rachel-nichols/) > [“Pumpkin Flavor Latte Scrub   Ingredients 1 ½ cups of brown sugar 2 tablespoons of ground coffee 1-2 tablespoons of pumpkin spice ¾ -1…](https://sms4smile.com/quotes/kate-hilton/pumpkin-flavor-latte-scrub-ingredients-1-cups-of-brown-sugar-2/) Kate Hilton [Browse all 34,183 Food quotes ](https://sms4smile.com/quotes/about/food/) ```json { "@context": "https://schema.org", "@graph": [ { "@type": "Quotation", "text": "“when the omega-3 fats EPA and DHA are oxidized, they significantly activate the Nrf2 pathway. For”", "creator": { "@type": "Person", "name": "David Perlmutter" }, "isPartOf": { "@id": "https://sms4smile.com/quotes/#website" }, "url": "https://sms4smile.com/quotes/david-perlmutter/when-the-omega-3-fats-epa-and-dha-are-oxidized-they-significantly/", "about": { "@type": "Thing", "name": "Food" }, "@id": "https://sms4smile.com/quotes/david-perlmutter/when-the-omega-3-fats-epa-and-dha-are-oxidized-they-significantly/#quotation", "image": { "@type": "ImageObject", "@id": "https://sms4smile.com/quotes/i/fab/david-perlmutter-2461_food_when-the-omega-3-fats-epa-and-dha-are-ox_1564473.png", "contentUrl": "https://sms4smile.com/quotes/i/fab/david-perlmutter-2461_food_when-the-omega-3-fats-epa-and-dha-are-ox_1564473.png", "url": "https://sms4smile.com/quotes/i/fab/david-perlmutter-2461_food_when-the-omega-3-fats-epa-and-dha-are-ox_1564473.png", "width": 1080, "height": 1080, "caption": "“when the omega-3 fats EPA and DHA are oxidized, they significantly activate the Nrf2 pathway. For” — David Perlmutter", "creditText": "SMS4Smile Quotes", "creator": { "@id": "https://sms4smile.com/quotes/#organization" } } }, { "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://sms4smile.com/" }, { "@type": "ListItem", "position": 2, "name": "Quotes", "item": "https://sms4smile.com/quotes/" }, { "@type": "ListItem", "position": 3, "name": "David Perlmutter", "item": "https://sms4smile.com/quotes/author/david-perlmutter/" }, { "@type": "ListItem", "position": 4, "name": "“when the omega-3 fats EPA and...", "item": "https://sms4smile.com/quotes/david-perlmutter/when-the-omega-3-fats-epa-and-dha-are-oxidized-they-significantly/" } ], "@id": "https://sms4smile.com/quotes/david-perlmutter/when-the-omega-3-fats-epa-and-dha-are-oxidized-they-significantly/#breadcrumb" }, { "@type": "WebSite", "@id": "https://sms4smile.com/quotes/#website", "name": "SMS4Smile Quotes", "url": "https://sms4smile.com/quotes/", "publisher": { "@id": "https://sms4smile.com/quotes/#organization" } }, { "@type": "Organization", "@id": "https://sms4smile.com/quotes/#organization", "name": "SMS4Smile Quotes", "url": "https://sms4smile.com/quotes/", "logo": { "@type": "ImageObject", "url": "https://sms4smile.com/quotes/wp-content/themes/sq/assets/icons/icon-512.png", "width": 512, "height": 512 } } ] } ```