--- title: "Meaning & Key Takeaway of: Researchers have known for some time now…" description: "\"Researchers have known for some time now that the cornerstone of all degenerative conditions, including brain disorders, is inflammation. But what they..." image: "https://sms4smile.com/quotes/i/f3c/david-perlmutter-2461_brain_researchers-have-known-for-some-time-now_353075.jpg" --- # Researchers have known for some time now that the… ![“Researchers have known for some time now that the cornerstone of all degenerative conditions, including brain disorders, is inflammation. But what they didn’t have documented until now are the instigators of that inflammation—the first missteps that prompt this deadly reaction. And what they are…” quote by David Perlmutter](https://sms4smile.com/quotes/i/f3c/david-perlmutter-2461_brain_researchers-have-known-for-some-time-now_353075.jpg) [Download](https://sms4smile.com/quotes/i/f3c/david-perlmutter-2461_brain_researchers-have-known-for-some-time-now_353075.jpg) [Open image](https://sms4smile.com/quotes/i/f3c/david-perlmutter-2461_brain_researchers-have-known-for-some-time-now_353075.jpg) > “Researchers have known for some time now that the cornerstone of all degenerative conditions, including brain disorders, is inflammation. But what they didn’t have documented until now are the instigators of that inflammation—the first missteps that prompt this deadly reaction. And what they are finding is that gluten, and a high-carbohydrate diet for that matter, are among the most prominent stimulators of inflammatory pathways that reach the brain.” [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) ## About This Quote This interpretation was drafted with AI assistance. It is one reading of the quote, not the author's own explanation. Inflammation drives many degenerative diseases, and dietary choices like gluten and high carbs trigger brain inflammation. **In simple terms:** Bad diets cause brain inflammation. Key Takeaway Avoid gluten and excess carbs to protect brain health. Themes nutrition brain health inflammation diet disease prevention Mood concerned motivated Type advice informative When to use this quote - personal nutrition planning - clinical counseling - public health policy - patient education Key Concepts Neuroinflammation metabolic triggers immune response Questions to Reflect On - How can you identify hidden gluten sources? - What alternative carbs support brain health? A Different Perspective Dietary changes alone may not reverse established inflammation. ★ ★ ★ ★ ★ No ratings yet [Brain](https://sms4smile.com/quotes/about/brain/) [Carbohydrates](https://sms4smile.com/quotes/about/carbohydrates/) [Disorder](https://sms4smile.com/quotes/about/disorder/) [Findings](https://sms4smile.com/quotes/about/findings/) [Firsts](https://sms4smile.com/quotes/about/firsts/) [Food](https://sms4smile.com/quotes/about/food/) [Gluten](https://sms4smile.com/quotes/about/gluten/) [Including Brain](https://sms4smile.com/quotes/about/including-brain-3257629/) [Inflammation](https://sms4smile.com/quotes/about/inflammation/) [Inflammation Missteps](https://sms4smile.com/quotes/about/inflammation-missteps-3257627/) [Inflammatory Pathways](https://sms4smile.com/quotes/about/inflammatory-pathways-3257626/) [Instigators](https://sms4smile.com/quotes/about/instigators/) [Matter](https://sms4smile.com/quotes/about/matter/) [Pathways](https://sms4smile.com/quotes/about/pathways/) [Reactions](https://sms4smile.com/quotes/about/reactions/) [Science](https://sms4smile.com/quotes/about/science/) [Stimulators Inflammatory](https://sms4smile.com/quotes/about/stimulators-inflammatory-3257628/) [Time](https://sms4smile.com/quotes/about/time/) ## Related quotes > [Inflammation is the cornerstone of Alzheimer's disease and Parkinson's, multiple sclerosis - all of the neurodegenerative diseases are really predicated on inflammation.](https://sms4smile.com/quotes/david-perlmutter/inflammation-is-the-cornerstone-of-alzheimer-s-disease-and-parkinson/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“Wouldn't you know it. I bring a man to life and forget all about including a brain that will make sense of any damn…](https://sms4smile.com/quotes/zana-fraillon/wouldn-t-you-know-it-i-bring-a-man-to-life-and-forget-all-about/) [Zana Fraillon](https://sms4smile.com/quotes/author/zana-fraillon/) > [“Scientists have documented time and time again that C-reactive protein—a commonly used laboratory marker of inflammation—is lower among people who keep an exercise routine.”](https://sms4smile.com/quotes/david-perlmutter/scientists-have-documented-time-and-time-again-that-c-reactive/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“This leading-edge research echoes what ancient wisdom has always known: that each organ of the body, including the brain, speaks its own “thoughts,” “feelings,”…](https://sms4smile.com/quotes/ann-frederick/this-leading-edge-research-echoes-what-ancient-wisdom-has-always/) [Ann Frederick](https://sms4smile.com/quotes/author/ann-frederick/) > [“Exposure to nature not only helps with creativity, but it may also lower levels of Interleukin-6 (IL-6), a molecule associated with inflammation in the…](https://sms4smile.com/quotes/brad-stulberg/exposure-to-nature-not-only-helps-with-creativity-but-it-may-also/) [Brad Stulberg](https://sms4smile.com/quotes/author/brad-stulberg/) > [Take charge of hidden, sneaky sources of chronic inflammation that can trigger illness and disease by wearing comfortable shoes daily, getting an annual flu…](https://sms4smile.com/quotes/david-agus/take-charge-of-hidden-sneaky-sources-of-chronic-inflammation-that-can/) [David Agus](https://sms4smile.com/quotes/author/david-agus/) > [No matter how valuable you are and your ideas, fools will certainly play both of you down, so exclude yourselves from the inflammatory environs…](https://sms4smile.com/quotes/michael-bassey-johnson/no-matter-how-valuable-you-are-and-your-ideas-fools-will-certainly/) [Michael Bassey Johnson](https://sms4smile.com/quotes/author/michael-bassey-johnson/) > [“Chronic     Your body’s initial, short-term response to damage. Think of acute inflammation as the cleanup before the rebuilding. It decreases quickly as your body…](https://sms4smile.com/quotes/dallas-hartwig/chronic-your-body-s-initial-short-term-response-to-damage-think-of/) [Dallas Hartwig](https://sms4smile.com/quotes/author/dallas-hartwig/) > [“In whatever disease sleep is laborious, it is a deadly symptom; but if sleep does good, it is not deadly.”](https://sms4smile.com/quotes/hippocrates/in-whatever-disease-sleep-is-laborious-it-is-a-deadly-symptom-but-if/) [Hippocrates](https://sms4smile.com/quotes/author/hippocrates/) > [“what is at the root of lifestyle-related diseases and conditions like heart disease and stroke? Take one guess. Systemic inflammation.”](https://sms4smile.com/quotes/melissa-hartwig/what-is-at-the-root-of-lifestyle-related-diseases-and-conditions-like/) [Melissa Hartwig](https://sms4smile.com/quotes/author/melissa-hartwig/) > [Lectins enter our our joints, our nerve junctions, the lining of our blood vessels and our brain where they incite inflammation and autoimmune diseases.](https://sms4smile.com/quotes/steven-gundry/lectins-enter-our-our-joints-our-nerve-junctions-the-lining-of-our/) [Steven Gundry](https://sms4smile.com/quotes/author/steven-gundry/) > [“When it comes to pain and inflammation, the food you consume plays a role. You see, food is a critical piece of the puzzle…](https://sms4smile.com/quotes/anonymous/when-it-comes-to-pain-and-inflammation-the-food-you-consume-plays-a/) [Anonymous](https://sms4smile.com/quotes/author/anonymous/) > [“body’s initial, short-term response to damage. Think of acute inflammation as the cleanup before the rebuilding. It decreases”](https://sms4smile.com/quotes/dallas-hartwig/body-s-initial-short-term-response-to-damage-think-of-acute/) [Dallas Hartwig](https://sms4smile.com/quotes/author/dallas-hartwig/) > [“What NFL Football Players and Nuns Can Teach Us about Deadly Inflammation—and How to Control It”](https://sms4smile.com/quotes/david-b-agus/what-nfl-football-players-and-nuns-can-teach-us-about-deadly/) [David B. Agus](https://sms4smile.com/quotes/author/david-b-agus/) > [It comes down to inflammation and how do you keep the inflammation down during the season. You can gain back a day just based…](https://sms4smile.com/quotes/cooper-kupp/it-comes-down-to-inflammation-and-how-do-you-keep-the-inflammation/) [Cooper Kupp](https://sms4smile.com/quotes/author/cooper-kupp/) ## More by David Perlmutter > [“if you cannot control your hunger and appetite, good luck managing your blood chemistry, metabolism, waistline, and, in the bigger picture, the prospect of…](https://sms4smile.com/quotes/david-perlmutter/if-you-cannot-control-your-hunger-and-appetite-good-luck-managing/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“Nine times out of ten, people pick the wrong food. 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Some people, however, don’t experience obvious signs of gastrointestinal trouble,…](https://sms4smile.com/quotes/david-perlmutter/those-who-experience-symptoms-complain-of-abdominal-pain-nausea/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [Saturated fat is a fundamental building block for brain cells. It's certainly interesting to consider that one of the richest sources of saturated fat…](https://sms4smile.com/quotes/david-perlmutter/saturated-fat-is-a-fundamental-building-block-for-brain-cells-it-s/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“THE GLUTEN POLICE The following grains and starches contain gluten: barley bulgur couscous farina graham flour kamut matzo rye semolina spelt triticale wheat wheat…](https://sms4smile.com/quotes/david-perlmutter/the-gluten-police-the-following-grains-and-starches-contain-gluten/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“people with celiac have significantly increased production of free radicals, and they exhibit free radical damage to their fat, protein, and even DNA.16 In…](https://sms4smile.com/quotes/david-perlmutter/people-with-celiac-have-significantly-increased-production-of-free/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“The bile salts secreted by the gallbladder, which are needed for the digestion of fat and, therefore, the absorption of fat-soluble vitamins like A,…](https://sms4smile.com/quotes/david-perlmutter/the-bile-salts-secreted-by-the-gallbladder-which-are-needed-for-the/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“According to the latest research, we owe our tremendous brains to the need to think… and the need to run.”](https://sms4smile.com/quotes/david-perlmutter/according-to-the-latest-research-we-owe-our-tremendous-brains-to-the/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [Most grain foods, whether we're talking about quinoa, amaranth, the very popular grains of the day - the reality is they still are associated…](https://sms4smile.com/quotes/david-perlmutter/most-grain-foods-whether-we-re-talking-about-quinoa-amaranth-the-very/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“reduce the risk of LDL oxidation—not necessarily levels of LDL itself. 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Never eat what Dr. Casey Means…](https://sms4smile.com/quotes/david-perlmutter/what-you-eat-when-you-eat-matter-but-so-does-what-order-you-eat-your/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“The results of the study revealed that those individuals in the lowest 10 percent of daily physical activity had a 230 percent increased risk…](https://sms4smile.com/quotes/david-perlmutter/the-results-of-the-study-revealed-that-those-individuals-in-the/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) [Explore all 163 David Perlmutter quotes ](https://sms4smile.com/quotes/author/david-perlmutter/) ## More Brain quotes > [The brain abhors discrepancies.](https://sms4smile.com/quotes/vilayanur-s-ramachandran/the-brain-abhors-discrepancies/) [Vilayanur S. Ramachandran](https://sms4smile.com/quotes/author/vilayanur-s-ramachandran/) > [In some circles where very heavy people think they have very heavy brains, words like "charming" and "clever" and "pretty" are all put-downs; all…](https://sms4smile.com/quotes/andy-warhol/in-some-circles-where-very-heavy-people-think-they-have-very-heavy/) [Andy Warhol](https://sms4smile.com/quotes/author/andy-warhol/) > [Let me tell you that atheism has never painted a masterpiece. Atheism has never dispelled fear. Atheism has never healed a disease; faith in…](https://sms4smile.com/quotes/john-hagee/let-me-tell-you-that-atheism-has-never-painted-a-masterpiece-atheism/) [John Hagee](https://sms4smile.com/quotes/author/john-hagee/) > [down with ought with because with every brain that thinks it thinks nor dares to feel.](https://sms4smile.com/quotes/anonymous/down-with-ought-with-because-with-every-brain-that-thinks-it-thinks/) [Anonymous](https://sms4smile.com/quotes/author/anonymous/) > [To explicate the uses of the Brain seems as difficult a task as to paint the Soul, of which it is commonly said, that…](https://sms4smile.com/quotes/thomas-willis/to-explicate-the-uses-of-the-brain-seems-as-difficult-a-task-as-to/) [Thomas Willis](https://sms4smile.com/quotes/author/thomas-willis/) > [I prefer the word 'musician.' I'm a musician and a composer. I have a problem with the word 'artist.' I don't know if it's…](https://sms4smile.com/quotes/stromae/i-prefer-the-word-musician-i-m-a-musician-and-a-composer-i-have-a/) [Stromae](https://sms4smile.com/quotes/author/stromae/) > [Thinking of sex provides enough mental stimulation to reduce risk of diseases that damage the brain.](https://sms4smile.com/quotes/anonymous/thinking-of-sex-provides-enough-mental-stimulation-to-reduce-risk-of/) [Anonymous](https://sms4smile.com/quotes/author/anonymous/) > [My writing routine is: get son off to school and sit down at 8 A.M. 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