--- title: "Meaning & Key Takeaway of: Inflammation is the cornerstone of…" description: "\"Inflammation is the cornerstone of Alzheimer's disease and Parkinson's, multiple sclerosis - all of the neurodegenerative diseases are really predicate..." image: "https://sms4smile.com/quotes/i/6d8/david-perlmutter-2461_alzheimer_inflammation-is-the-cornerstone-of-alzhe_52887.png" --- # Inflammation is the cornerstone of Alzheimer's disease and… ![“Inflammation is the cornerstone of Alzheimer's disease and Parkinson's, multiple sclerosis - all of the neurodegenerative diseases are really predicated on inflammation.” quote by David Perlmutter](https://sms4smile.com/quotes/i/6d8/david-perlmutter-2461_alzheimer_inflammation-is-the-cornerstone-of-alzhe_52887.png) [Download](https://sms4smile.com/quotes/i/6d8/david-perlmutter-2461_alzheimer_inflammation-is-the-cornerstone-of-alzhe_52887.png) [Open image](https://sms4smile.com/quotes/i/6d8/david-perlmutter-2461_alzheimer_inflammation-is-the-cornerstone-of-alzhe_52887.png) > “Inflammation is the cornerstone of Alzheimer's disease and Parkinson's, multiple sclerosis - all of the neurodegenerative diseases are really predicated on inflammation.” [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) ## About This Quote This interpretation was drafted with AI assistance. It is one reading of the quote, not the author's own explanation. Neurodegenerative disorders share a common underlying process of chronic inflammation, which drives disease progression. **In simple terms:** Inflammation drives neurodegeneration. Key Takeaway Targeting inflammation could alter disease course. Themes Neurobiology Inflammation Disease Mechanisms Aging Therapeutics Mood Concerned Hopeful Urgent Type Scientific Clinical Educational When to use this quote - Clinical research - Drug development - Patient counseling - Public health policy - Medical education Key Concepts Neuroinflammation Protein Aggregation Oxidative Stress Immune Dysregulation Practical Applications - Develop anti‑inflammatory therapies - Design preventive lifestyle programs Questions to Reflect On - How might anti‑inflammatory strategies change disease outcomes? - What biomarkers best reflect neuroinflammatory activity? A Different Perspective Some evidence suggests genetic and metabolic factors also play primary roles, not just inflammation. ★ ★ ★ ★ ★ No ratings yet [Alzheimer](https://sms4smile.com/quotes/about/alzheimer/) [Disease](https://sms4smile.com/quotes/about/disease/) [Inflammation](https://sms4smile.com/quotes/about/inflammation/) [Multiple sclerosis](https://sms4smile.com/quotes/about/multiple-sclerosis/) [Parkinson](https://sms4smile.com/quotes/about/parkinson/) ## Related quotes > [“Scientists have documented time and time again that C-reactive protein—a commonly used laboratory marker of inflammation—is lower among people who keep an exercise routine.”](https://sms4smile.com/quotes/david-perlmutter/scientists-have-documented-time-and-time-again-that-c-reactive/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [Researchers have known for some time now that the cornerstone of all degenerative conditions, including brain disorders, is inflammation. But what they didn’t have…](https://sms4smile.com/quotes/david-perlmutter/researchers-have-known-for-some-time-now-that-the-cornerstone-of-all/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [Take charge of hidden, sneaky sources of chronic inflammation that can trigger illness and disease by wearing comfortable shoes daily, getting an annual flu…](https://sms4smile.com/quotes/david-agus/take-charge-of-hidden-sneaky-sources-of-chronic-inflammation-that-can/) [David Agus](https://sms4smile.com/quotes/author/david-agus/) > [“In whatever disease sleep is laborious, it is a deadly symptom; but if sleep does good, it is not deadly.”](https://sms4smile.com/quotes/hippocrates/in-whatever-disease-sleep-is-laborious-it-is-a-deadly-symptom-but-if/) [Hippocrates](https://sms4smile.com/quotes/author/hippocrates/) > [“what is at the root of lifestyle-related diseases and conditions like heart disease and stroke? Take one guess. 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It decreases quickly as your body…](https://sms4smile.com/quotes/dallas-hartwig/chronic-your-body-s-initial-short-term-response-to-damage-think-of/) Dallas Hartwig > [No matter how valuable you are and your ideas, fools will certainly play both of you down, so exclude yourselves from the inflammatory environs…](https://sms4smile.com/quotes/michael-bassey-johnson/no-matter-how-valuable-you-are-and-your-ideas-fools-will-certainly/) [Michael Bassey Johnson](https://sms4smile.com/quotes/author/michael-bassey-johnson/) > [“Multiple sclerosis is a chronic disease affecting the central nervous system (CNS: the brain, spinal cord, and optic nerves). It is not contagious.”](https://sms4smile.com/quotes/nancy-j-holland/multiple-sclerosis-is-a-chronic-disease-affecting-the-central-nervous/) Nancy J. Holland > [I continually still fight every day for my life, not only still battling mental health problems but battling multiple sclerosis, which also has depression…](https://sms4smile.com/quotes/jennifer-holliday/i-continually-still-fight-every-day-for-my-life-not-only-still/) [Jennifer Holliday](https://sms4smile.com/quotes/author/jennifer-holliday/) ## More by David Perlmutter > [“if you cannot control your hunger and appetite, good luck managing your blood chemistry, metabolism, waistline, and, in the bigger picture, the prospect of…](https://sms4smile.com/quotes/david-perlmutter/if-you-cannot-control-your-hunger-and-appetite-good-luck-managing/) [David Perlmutter](https://sms4smile.com/quotes/author/david-perlmutter/) > [“Nine times out of ten, people pick the wrong food. 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