--- title: "Meaning & Key Takeaway of: anterior medial prefrontal and posterior…" description: "\"“anterior medial prefrontal and posterior cingulate cortices (amPFC, PCC)—while”\" — David DiSalvo" image: "https://sms4smile.com/quotes/i/ecb/david-disalvo-3662_cortex_anterior-medial-prefrontal-and-posterior_2858610.jpg" --- # anterior medial prefrontal and posterior cingulate… ![“anterior medial prefrontal and posterior cingulate cortices (amPFC, PCC)—while” quote by David DiSalvo](https://sms4smile.com/quotes/i/ecb/david-disalvo-3662_cortex_anterior-medial-prefrontal-and-posterior_2858610.jpg) [Download](https://sms4smile.com/quotes/i/ecb/david-disalvo-3662_cortex_anterior-medial-prefrontal-and-posterior_2858610.jpg) [Open image](https://sms4smile.com/quotes/i/ecb/david-disalvo-3662_cortex_anterior-medial-prefrontal-and-posterior_2858610.jpg) > ““anterior medial prefrontal and posterior cingulate cortices (amPFC, PCC)—while”” [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) ## About This Quote This interpretation was drafted with AI assistance. It is one reading of the quote, not the author's own explanation. The amPFC and PCC are involved in self‑related processing while... **In simple terms:** Specific brain areas handle self‑thought. Key Takeaway Study brain networks of self. Themes neuroscience self brain regions Mood analytical technical Type scientific academic When to use this quote - clinical research - mental health - education Key Concepts cognitive science psychology Questions to Reflect On - How does self‑processing affect behavior? - What disorders involve these regions? A Different Perspective Complex interactions are not fully understood. ★ ★ ★ ★ ★ No ratings yet [Cingulate Cortices](https://sms4smile.com/quotes/about/cingulate-cortices-3844973/) [Cortex](https://sms4smile.com/quotes/about/cortex-283580/) [Cortices Ampfc](https://sms4smile.com/quotes/about/cortices-ampfc-3844972/) [Medial Prefrontal](https://sms4smile.com/quotes/about/medial-prefrontal-3844976/) [Posterior Cingulate](https://sms4smile.com/quotes/about/posterior-cingulate-3844974/) [Prefrontal Posterior](https://sms4smile.com/quotes/about/prefrontal-posterior-3844975/) ## Related quotes > [“activated when recalling a personal memory—the posterior cingulate gyrus, parahippocampal gyrus, and left occipital lobe—are also active when thinking about a future event.”](https://sms4smile.com/quotes/david-disalvo/activated-when-recalling-a-personal-memory-the-posterior-cingulate/) [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) > [“even a small amount of ambiguity triggers increased activity in the amygdalae—two deep brain structures that play a major role in our response to…](https://sms4smile.com/quotes/david-disalvo/even-a-small-amount-of-ambiguity-triggers-increased-activity-in-the/) [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) > [“As the level of ambiguity increases, amygdalae activity continues to increase, and ventral striatum activity continues to decrease.”](https://sms4smile.com/quotes/david-disalvo/as-the-level-of-ambiguity-increases-amygdalae-activity-continues-to/) [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) > [“amygdalae filter through the information to determine its threat-level significance and mobilizes a response.”](https://sms4smile.com/quotes/david-disalvo/amygdalae-filter-through-the-information-to-determine-its-threat/) [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) > [“Powerful support for an amygdaloid role in fear processing comes from post-traumatic stress disorder (PTSD). In PTSD sufferers the amygdala is overreactive to mildly…](https://sms4smile.com/quotes/robert-m-sapolsky/powerful-support-for-an-amygdaloid-role-in-fear-processing-comes-from/) [Robert M. Sapolsky](https://sms4smile.com/quotes/author/robert-m-sapolsky/) > [“The frontal lobes are one of the most important parts of the cortex to understand.”](https://sms4smile.com/quotes/catherine-m-pittman/the-frontal-lobes-are-one-of-the-most-important-parts-of-the-cortex/) [Catherine M. Pittman](https://sms4smile.com/quotes/author/catherine-m-pittman/) > [“Moderate, transient stress (i.e., the good, stimulatory stress) promotes hippocampal LTP, while prolonged stress disrupts it and promotes LTD—one reason why cognition tanks at…](https://sms4smile.com/quotes/robert-m-sapolsky/moderate-transient-stress-i-e-the-good-stimulatory-stress-promotes/) [Robert M. Sapolsky](https://sms4smile.com/quotes/author/robert-m-sapolsky/) > [“It’s not until the non-NMDA has been stimulated over and over by a long train of glutamate release, allowing enough sodium to flow in,…](https://sms4smile.com/quotes/robert-m-sapolsky/it-s-not-until-the-non-nmda-has-been-stimulated-over-and-over-by-a/) [Robert M. Sapolsky](https://sms4smile.com/quotes/author/robert-m-sapolsky/) > [“Chapter 3 discusses some unsettling research—stick your average person in a brain scanner, and show him a picture of someone of another race for…](https://sms4smile.com/quotes/robert-m-sapolsky/chapter-3-discusses-some-unsettling-research-stick-your-average/) [Robert M. Sapolsky](https://sms4smile.com/quotes/author/robert-m-sapolsky/) > [Brains distinguish between an Us and a Them in a fraction of a second. Subliminal processing of a Them activates the amygdala and insular…](https://sms4smile.com/quotes/robert-m-sapolsky/brains-distinguish-between-an-us-and-a-them-in-a-fraction-of-a-second/) [Robert M. Sapolsky](https://sms4smile.com/quotes/author/robert-m-sapolsky/) > [“The amygdala can accomplish its quick response because of the special properties of another nucleus within it: the central nucleus.”](https://sms4smile.com/quotes/catherine-m-pittman/the-amygdala-can-accomplish-its-quick-response-because-of-the-special/) [Catherine M. Pittman](https://sms4smile.com/quotes/author/catherine-m-pittman/) > [Spatial working memory is impaired by stress.](https://sms4smile.com/quotes/richard-davidson/spatial-working-memory-is-impaired-by-stress/) [Richard Davidson](https://sms4smile.com/quotes/author/richard-davidson/) > [“Most broadly, the PFC chooses between conflicting options—Coke or Pepsi; blurting out what you really think or restraining yourself; pulling the trigger or not.…](https://sms4smile.com/quotes/robert-m-sapolsky/most-broadly-the-pfc-chooses-between-conflicting-options-coke-or/) [Robert M. Sapolsky](https://sms4smile.com/quotes/author/robert-m-sapolsky/) > [“We process emotionally salient information more rapidly and automatically, but with less accuracy. Frontal function—working memory, impulse control, executive decision making, risk assessment, and…](https://sms4smile.com/quotes/robert-m-sapolsky/we-process-emotionally-salient-information-more-rapidly-and/) [Robert M. Sapolsky](https://sms4smile.com/quotes/author/robert-m-sapolsky/) > [Visual cortex is fundamentally a machine whose job is to generate a model of the world.](https://sms4smile.com/quotes/david-eagleman/visual-cortex-is-fundamentally-a-machine-whose-job-is-to-generate-a/) [David Eagleman](https://sms4smile.com/quotes/author/david-eagleman/) ## More by David DiSalvo > [“The flip side of this reality is that our big brains, advanced as they are, come with an array of complex shortcomings and are…](https://sms4smile.com/quotes/david-disalvo/the-flip-side-of-this-reality-is-that-our-big-brains-advanced-as-they/) [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) > [“Participants who anticipated more rapid feedback scored the highest on the test.”](https://sms4smile.com/quotes/david-disalvo/participants-who-anticipated-more-rapid-feedback-scored-the-highest/) [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) > [“The best way to think of how our brains frame information is to imagine a picture frame, except unlike a normal frame, this one…](https://sms4smile.com/quotes/david-disalvo/the-best-way-to-think-of-how-our-brains-frame-information-is-to/) [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) > [“the amPFC and PCC were shown to play a large role in self-referential thinking and autobiographical memory (essentially, the “me” part of your brain).”](https://sms4smile.com/quotes/david-disalvo/the-ampfc-and-pcc-were-shown-to-play-a-large-role-in-self-referential/) [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) > [“those who ask themselves whether they will perform a task generally do better than those who tell themselves that they will.”](https://sms4smile.com/quotes/david-disalvo/those-who-ask-themselves-whether-they-will-perform-a-task-generally/) [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) > [“words, for our brains, reality equals relevance.”](https://sms4smile.com/quotes/david-disalvo/words-for-our-brains-reality-equals-relevance/) [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) > [“In German, bridge (die brucke) is a feminine noun; in Spanish, bridge (el puente) is a masculine noun. Boroditsky found that when asked to…](https://sms4smile.com/quotes/david-disalvo/in-german-bridge-die-brucke-is-a-feminine-noun-in-spanish-bridge-el/) [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) > [“selective attention,” also called “selectivity bias”—the tendency to orient oneself toward and process information from only one part of our environment to the exclusion…](https://sms4smile.com/quotes/david-disalvo/selective-attention-also-called-selectivity-bias-the-tendency-to/) [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) > [“great deal of “green” marketing is predicated on the assumption that people will buy a green product to make themselves feel better about moral…](https://sms4smile.com/quotes/david-disalvo/great-deal-of-green-marketing-is-predicated-on-the-assumption-that/) [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) > [“appears that our first instinct is for idleness, but when given an excuse to be busy (even a meaningless one), we're liable to act…](https://sms4smile.com/quotes/david-disalvo/appears-that-our-first-instinct-is-for-idleness-but-when-given-an/) [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) > [“The reason that persuasive messages are short, pithy, and digestible in seconds is that we process them so quickly that they become familiar without…](https://sms4smile.com/quotes/david-disalvo/the-reason-that-persuasive-messages-are-short-pithy-and-digestible-in/) [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) > [“schema (singular form of schemata) is like a mental map of concepts that hangs together by association.”](https://sms4smile.com/quotes/david-disalvo/schema-singular-form-of-schemata-is-like-a-mental-map-of-concepts/) [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) > [“Specifically, a web of neurons—dubbed the “default network”—spanning three brain regions (the medial prefrontal cortex, the posterior cingulate cortex, and the parietal cortex) are…](https://sms4smile.com/quotes/david-disalvo/specifically-a-web-of-neurons-dubbed-the-default-network-spanning/) [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) > [“it's always on in the background but only takes first chair in our brains when we're not focused on anything in particular.”](https://sms4smile.com/quotes/david-disalvo/it-s-always-on-in-the-background-but-only-takes-first-chair-in-our/) [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) > [“Our expectations for what we should be able to recall are hardly in line with what our brains are capable of processing—which, by the…](https://sms4smile.com/quotes/david-disalvo/our-expectations-for-what-we-should-be-able-to-recall-are-hardly-in/) [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) [Explore all 125 David DiSalvo quotes ](https://sms4smile.com/quotes/author/david-disalvo/) ## More Cortex quotes > [Visual cortex is fundamentally a machine whose job is to generate a model of the world.](https://sms4smile.com/quotes/david-eagleman/visual-cortex-is-fundamentally-a-machine-whose-job-is-to-generate-a/) [David Eagleman](https://sms4smile.com/quotes/author/david-eagleman/) > [“We process emotionally salient information more rapidly and automatically, but with less accuracy. Frontal function—working memory, impulse control, executive decision making, risk assessment, and…](https://sms4smile.com/quotes/robert-m-sapolsky/we-process-emotionally-salient-information-more-rapidly-and/) [Robert M. Sapolsky](https://sms4smile.com/quotes/author/robert-m-sapolsky/) > [“Most broadly, the PFC chooses between conflicting options—Coke or Pepsi; blurting out what you really think or restraining yourself; pulling the trigger or not.…](https://sms4smile.com/quotes/robert-m-sapolsky/most-broadly-the-pfc-chooses-between-conflicting-options-coke-or/) [Robert M. Sapolsky](https://sms4smile.com/quotes/author/robert-m-sapolsky/) > [Spatial working memory is impaired by stress.](https://sms4smile.com/quotes/richard-davidson/spatial-working-memory-is-impaired-by-stress/) [Richard Davidson](https://sms4smile.com/quotes/author/richard-davidson/) > [“The amygdala can accomplish its quick response because of the special properties of another nucleus within it: the central nucleus.”](https://sms4smile.com/quotes/catherine-m-pittman/the-amygdala-can-accomplish-its-quick-response-because-of-the-special/) [Catherine M. Pittman](https://sms4smile.com/quotes/author/catherine-m-pittman/) > [Brains distinguish between an Us and a Them in a fraction of a second. Subliminal processing of a Them activates the amygdala and insular…](https://sms4smile.com/quotes/robert-m-sapolsky/brains-distinguish-between-an-us-and-a-them-in-a-fraction-of-a-second/) [Robert M. Sapolsky](https://sms4smile.com/quotes/author/robert-m-sapolsky/) > [“Chapter 3 discusses some unsettling research—stick your average person in a brain scanner, and show him a picture of someone of another race for…](https://sms4smile.com/quotes/robert-m-sapolsky/chapter-3-discusses-some-unsettling-research-stick-your-average/) [Robert M. Sapolsky](https://sms4smile.com/quotes/author/robert-m-sapolsky/) > [“It’s not until the non-NMDA has been stimulated over and over by a long train of glutamate release, allowing enough sodium to flow in,…](https://sms4smile.com/quotes/robert-m-sapolsky/it-s-not-until-the-non-nmda-has-been-stimulated-over-and-over-by-a/) [Robert M. Sapolsky](https://sms4smile.com/quotes/author/robert-m-sapolsky/) > [“Moderate, transient stress (i.e., the good, stimulatory stress) promotes hippocampal LTP, while prolonged stress disrupts it and promotes LTD—one reason why cognition tanks at…](https://sms4smile.com/quotes/robert-m-sapolsky/moderate-transient-stress-i-e-the-good-stimulatory-stress-promotes/) [Robert M. Sapolsky](https://sms4smile.com/quotes/author/robert-m-sapolsky/) > [“The frontal lobes are one of the most important parts of the cortex to understand.”](https://sms4smile.com/quotes/catherine-m-pittman/the-frontal-lobes-are-one-of-the-most-important-parts-of-the-cortex/) [Catherine M. Pittman](https://sms4smile.com/quotes/author/catherine-m-pittman/) > [“Powerful support for an amygdaloid role in fear processing comes from post-traumatic stress disorder (PTSD). In PTSD sufferers the amygdala is overreactive to mildly…](https://sms4smile.com/quotes/robert-m-sapolsky/powerful-support-for-an-amygdaloid-role-in-fear-processing-comes-from/) [Robert M. Sapolsky](https://sms4smile.com/quotes/author/robert-m-sapolsky/) > [“Logically, when the amygdala wants to mobilize a behavior—say, fleeing—it talks to the frontal cortex, seeking its executive approval. But if sufficiently aroused, the…](https://sms4smile.com/quotes/robert-m-sapolsky/logically-when-the-amygdala-wants-to-mobilize-a-behavior-say-fleeing/) [Robert M. Sapolsky](https://sms4smile.com/quotes/author/robert-m-sapolsky/) > [“Joseph LeDoux at New York University has shown how the BLA learns fear.fn14,20 Expose a rat to an innate trigger of fear—a shock. When…](https://sms4smile.com/quotes/robert-m-sapolsky/joseph-ledoux-at-new-york-university-has-shown-how-the-bla-learns/) [Robert M. Sapolsky](https://sms4smile.com/quotes/author/robert-m-sapolsky/) > [“amygdalae filter through the information to determine its threat-level significance and mobilizes a response.”](https://sms4smile.com/quotes/david-disalvo/amygdalae-filter-through-the-information-to-determine-its-threat/) [David DiSalvo](https://sms4smile.com/quotes/author/david-disalvo/) > [“The quick reaction that results from the amygdala pathway is typically called the fight-or-flight response.”](https://sms4smile.com/quotes/catherine-m-pittman/the-quick-reaction-that-results-from-the-amygdala-pathway-is/) [Catherine M. Pittman](https://sms4smile.com/quotes/author/catherine-m-pittman/) [Browse all 79 Cortex quotes ](https://sms4smile.com/quotes/about/cortex-283580/) ```json { "@context": "https://schema.org", "@graph": [ { "@type": "Quotation", "text": "“anterior medial prefrontal and posterior cingulate cortices (amPFC, PCC)—while”", "creator": { "@type": "Person", "name": "David DiSalvo" }, "isPartOf": { "@id": "https://sms4smile.com/quotes/#website" }, "url": "https://sms4smile.com/quotes/david-disalvo/anterior-medial-prefrontal-and-posterior-cingulate-cortices-ampfc-pcc/", "about": { "@type": "Thing", "name": "Cortex" }, "@id": "https://sms4smile.com/quotes/david-disalvo/anterior-medial-prefrontal-and-posterior-cingulate-cortices-ampfc-pcc/#quotation", "image": { "@type": "ImageObject", "@id": "https://sms4smile.com/quotes/i/ecb/david-disalvo-3662_cortex_anterior-medial-prefrontal-and-posterior_2858610.jpg", "contentUrl": "https://sms4smile.com/quotes/i/ecb/david-disalvo-3662_cortex_anterior-medial-prefrontal-and-posterior_2858610.jpg", "url": "https://sms4smile.com/quotes/i/ecb/david-disalvo-3662_cortex_anterior-medial-prefrontal-and-posterior_2858610.jpg", "width": 1080, "height": 1080, "caption": "“anterior medial prefrontal and posterior cingulate cortices (amPFC, PCC)—while” — David DiSalvo", "creditText": "SMS4Smile Quotes", "creator": { "@id": "https://sms4smile.com/quotes/#organization" } } }, { "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://sms4smile.com/" }, { "@type": "ListItem", "position": 2, "name": "Quotes", "item": "https://sms4smile.com/quotes/" }, { "@type": "ListItem", "position": 3, "name": "David DiSalvo", "item": "https://sms4smile.com/quotes/author/david-disalvo/" }, { "@type": "ListItem", "position": 4, "name": "“anterior medial prefrontal and posterior cingulate...", "item": "https://sms4smile.com/quotes/david-disalvo/anterior-medial-prefrontal-and-posterior-cingulate-cortices-ampfc-pcc/" } ], "@id": "https://sms4smile.com/quotes/david-disalvo/anterior-medial-prefrontal-and-posterior-cingulate-cortices-ampfc-pcc/#breadcrumb" }, { "@type": "WebSite", "@id": "https://sms4smile.com/quotes/#website", "name": "SMS4Smile Quotes", "url": "https://sms4smile.com/quotes/", "publisher": { "@id": "https://sms4smile.com/quotes/#organization" } }, { "@type": "Organization", "@id": "https://sms4smile.com/quotes/#organization", "name": "SMS4Smile Quotes", "url": "https://sms4smile.com/quotes/", "logo": { "@type": "ImageObject", "url": "https://sms4smile.com/quotes/wp-content/themes/sq/assets/icons/icon-512.png", "width": 512, "height": 512 } } ] } ```